Biotech startups are using the body's own microorganisms to prevent and treat diseases, including cancer.

Healthcare companies are paying attention to the microbiome, i.e. the world of microorganisms that inhabit the human body, with a new school of thought believing many conditions and diseases have a root cause in the gut bacteria in particular.

We identified 11 private companies working in the space, many of them leveraging sequencing and better understanding of bacterial communities to help promote wellness or create therapies for specific diseases and conditions, including cancer and inflammatory bowel syndrome. Here they are below, arranged in alphabetical order:

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Private Companies Working In The Microbiome
Company Description Total Funding (M) Select Investors
C3 Jian Biotech company focusing on diagnosing, treating, and preventing diseases relevant to the human microbiome (with a focus on oral health) $113 Delta Dental, Corvesta, Wyssta Investments
Eligo Bioscience Developing ultra-precise antibiotics to target harmful bacteria and sparing beneficial ones $2.2 Seventure Partners
Enterome Focusing on microbiome-related diseases such as Irritable Bowel Syndrome and metabolic diseases (diabetes and obesity) $23.8 Seventure Partners, Lundbeckfond Ventures, Danone
EpiBiome Precision microbiome engineering, creating therapies for humans and agriculture without the use of antibiotics $5.7 Illumina Accelerator
Evelo Therapeutics Company that seeks to create microbiome therapies for the treatment of cancer $35 Flagship Ventures
Evolve BioSystems Working to develop products that maintain healthy microbiomes in infants $9 Horizons Ventures, Tate & Lyle Ventures
ISOThrive Dietary supplement company with the goal of improving microbiome health $1.4 Undisclosed
Kallyope Cutting-edge technologies in sequencing, bioinformatics, neural imaging, cellular and molecular biology, and human genetics to provide an understanding of gut-brain biology $44 Lux Capital, Polaris Partners, The Column Group
Rebiotix Creating “Microbiota Restoration Therapy” to deliver live microbes into intestinal tracts to treat disease $30 Michael Berman, Quartis
Second Genome Clinical-stage company discovering and developing therapies for microbiome related diseases, focusing on inflammatory bowel disease $12.7 Morgenthaler Ventures, Wavepoint Ventures, Advanced Technology Ventures
uBiome Sequences, stores, and analyzes data related to the human microbiome $4.9 Andreessen Horowitz, BoxGroup, 500 Accelerator


Want more data on microbiome companies? Check out our private company database below.