Atomwise develops machine learning-based discovery engines and uses artificial intelligence (AI)-based neural networks to help discover new medicines. It predicts drug candidates for pharmaceutical companies, start-ups, and research institutions, and designs drugs using computational drug design. It was formerly known as Chematria. The company was founded in 2012 and is based in San Francisco, California.

SOM Biotech operates as a clinical-stage drug discovery and development company that focuses on the treatment of rare Central Nervous System disorders. The company utilizes an artificial intelligence platform to discover and develop drugs, with emphasis on orphan diseases and repurposing existing drugs for new therapeutic indications. SOM Biotech's lead product has completed Phase 2b trials for Huntington's Disease. It was founded in 2009 and is based in Barcelona, Spain.

NuMedii is a company focused on drug discovery within the biotechnology sector, utilizing data analysis and computational methods. They offer services that integrate sets of human, biological, pharmacological, and clinical data to identify drug candidates and biomarkers indicative of therapeutic efficacy. NuMedii's technology aims to support the development of new therapies. It was founded in 2008 and is based in Menlo Park, California.

Insitro is a data-driven drug discovery and development company that utilizes machine learning and high-throughput biology. The company has a machine learning platform that combines in vitro cellular data with human clinical data to identify insights and interventions in metabolism, oncology, and neuroscience. Insitro's approach uses technology to model disease states and design therapeutic interventions. It was founded in 2018 and is based in South San Francisco, California.

Aria Pharmaceuticals operates as a preclinical-stage pharmaceutical company that focuses on the discovery and development of novel, small-molecule therapies in the pharmaceutical industry. The company's main service is the development of new treatments for complex and hard-to-treat diseases using its proprietary symphony platform, which combines biomedical data and artificial intelligence to increase the success rates of drug discovery. Aria Pharmaceuticals primarily serves the healthcare sector, specifically targeting areas where new therapies are most needed. It was founded in 2014 and is based in Palo Alto, California.

Diverse Biotech is a clinical-stage biopharmaceutical company focused on developing therapeutics in the healthcare sector. The company specializes in drug conjugate therapies for cancer treatment by integrating synthetic cannabinoids with targeted therapeutics. Diverse Biotech is seeking partnerships and investments to advance its clinical programs and expand its drug platform. Diverse Biotech was formerly known as Leaf Vertical. It was founded in 2017 and is based in Miami, Florida.