Next Breath is involved in the development and analytical testing of inhalation and nasal drug products within the pharmaceutical industry. The company provides services including pharmaceutical formulation, CMC testing, finished batch release, post-approval stability, and regulatory submissions support. Next Breath serves pharmaceutical, biotech, and medical device companies with a focus on inhalation and nasal delivery systems. It is based in Baltimore, Maryland.

Corium International focuses on transdermal delivery systems within the healthcare sector. The company provides technologies for the delivery of both large and small molecules through the skin, using biodegradable microstructure patches and adhesive systems. These technologies are intended for proteins, peptides, vaccines, and other therapeutic agents that require transdermal administration. It was founded in 2002 and is based in Menlo Park, California.

BrainsGate is a medical device company focused on developing therapies for Central Nervous System (CNS) diseases. The company specializes in electrical stimulation of the Spheno-Palatine Ganglion (SPG) to enhance cerebral blood flow, with a current focus on treating acute ischemic stroke and chronic conditions such as vascular dementia. It was founded in 2000 and is based in Caesarea, Israel.

POINT Biomedical is a privately held pharmaceutical company, founded to pursue technologies related to imaging and drug delivery. POINT's core technology is based upon an ultrasonically responsive two-layer, biodegradable microsphere or biSphere. One of the most important features of this technology is the ability to noninvasively trigger the biSpheres to release their contents at sites within the body using externally generated pulses of ultrasound. From this basic platform, POINT is developing a pipeline of products that leverage the unique properties of the biSphere technology in the areas of imaging and therapeutics. POINT has initially focused development of this platform on the assessment of tissue specific blood flow. The lead product, CARDIOsphere, is a pharmaceutical agent that will enable cardiologists to perform myocardial perfusion imaging studies in the office setting using ultrasound rather than more expensive and cumbersome nuclear (or radioisotope) techniques.

R4 Vascular focuses on the design and manufacturing of vascular access products within the medical device industry. The company provides products that enable access to patient vasculature for the delivery of chemotherapy, blood products, antibiotics, drugs, or nutrition, primarily used by clinicians including oncologists, interventional radiologists, surgeons, and nurses. It is based in Hoboken, New Jersey.

Vapore focuses on consumer health and wellness, specializing in steam inhalation technology. The company offers handheld steam inhalers designed to provide relief from respiratory conditions such as allergies, sinus congestion, and colds, utilizing ultrapure steam. Vapore also markets skin rejuvenation devices that use light therapy to address aging signs. It was founded in 2001 and is based in Concord, California.