
Investments
303Portfolio Exits
91Funds
8Service Providers
1About SR One
SR One operates as a venture capital firm that invests globally in emerging life science companies that are pursuing innovative science which will significantly impact medical care. The company was formerly the corporate venture capital arm of GlaxoSmithKline and became a spinout. SR One has a team of investment professionals, located in the United States and the United Kingdom. It was founded in 1985 and is based in Conshohocken, Pennsylvania.

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Latest SR One News
Apr 5, 2023
Organisation > Second venture fund since spin out from GSK brings SR One total under management to over $1.5 billion > SR One will use this capital to continue supporting emerging biotechnology companies with the potential to translate innovative science into the next generation of novel medicines SR One, a transatlantic life sciences investment firm, today announced the close of its second fund (Fund II) at over $600 million, substantially exceeding its target of $500 million. Fund II is the second fund since SR One spun out from GlaxoSmithKline (GSK) in 2020 to form a fully independent investment firm. The diverse investor base of existing and new limited partners includes endowments, foundations, pharmaceutical companies, pension funds, sovereign wealth funds, and family o?ces. We received an incredible response to the fund and are grateful to our limited partners for their continued support and confidence in our team, said Simeon George, MD, Co- Founder and Chief Executive O?cer, SR One. SR One's model is built upon active collaboration and our ability to roll up our sleeves and help build value through multiple inflection points. We seek to partner with entrepreneurs building elite biotechnology companies, and we look forward to the potential development of new medicines for patients that Fund II may help bring to the market. With Fund II, SR One will continue to invest in biotechnology companies that have the potential to address significant gaps in the current treatment landscape. SR Ones investment strategy focuses on providing financial and direct operational support to help its portfolio companies advance programs through value-generating inflection points. We have built a team of seasoned investors and venture partners who I believe are well positioned to continue SR Ones history of productive investment, said Rajeev Dadoo, PhD, Managing Partner, SR One. With Fund II, we hope to continue to apply our tried and tested partnership model in an e?ort to benefit the companies in which we invest and, ultimately, the patients and families that they serve. Kirkland & Ellis acted as counsel to SR One for the fundraise. About SR One SR One is a transatlantic biotechnology venture capital firm, headquartered in the San Francisco Bay Area, that collaborates with entrepreneurs and investment partners in an e?ort to build elite biotechnology companies. The Companys mission is to translate innovative technologies and scientific discoveries into next-generation medicines with the potential to benefit patients with significant unmet medical needs. SR One leadership has worked together to build and invest in biotechnology companies for more than a decade. Working alongside the investment team, SR Ones venture partners bring deep operational experience to help company creation initiatives and support portfolio companies with financing and corporate strategies. Since the spin out from GSK in 2020, SR One has raised over $1 billion and founded and/or invested in over 20 companies. SR One has o?ces in Redwood City, CA, and Philadelphia, PA, in the US and London in the UK. For more information, connect at www.srone.com. Contacts
SR One Investments
303 Investments
SR One has made 303 investments. Their latest investment was in ADARx Pharmaceuticals as part of their Series B - III on January 1, 2023.

SR One Investments Activity

Date | Round | Company | Amount | New? | Co-Investors | Sources |
---|---|---|---|---|---|---|
1/20/2023 | Series B - III | ADARx Pharmaceuticals | $46M | No | 8 | |
12/6/2022 | Series C - II | Pulmocide | $52M | No | 5 | |
11/17/2022 | Series A | Rezo | $78M | Yes | 7 | |
10/13/2022 | Series B | |||||
9/29/2022 | Series A |
Date | 1/20/2023 | 12/6/2022 | 11/17/2022 | 10/13/2022 | 9/29/2022 |
---|---|---|---|---|---|
Round | Series B - III | Series C - II | Series A | Series B | Series A |
Company | ADARx Pharmaceuticals | Pulmocide | Rezo | ||
Amount | $46M | $52M | $78M | ||
New? | No | No | Yes | ||
Co-Investors | |||||
Sources | 8 | 5 | 7 |
SR One Portfolio Exits
91 Portfolio Exits
SR One has 91 portfolio exits. Their latest portfolio exit was Mineralys Therapeutics on February 10, 2023.
Date | Exit | Companies | Valuation Valuations are submitted by companies, mined from state filings or news, provided by VentureSource, or based on a comparables valuation model. | Acquirer | Sources |
---|---|---|---|---|---|
2/10/2023 | IPO | Public | 5 | ||
11/21/2022 | Acquired | 1 | |||
8/4/2022 | Acquired | 8 | |||
Date | 2/10/2023 | 11/21/2022 | 8/4/2022 | ||
---|---|---|---|---|---|
Exit | IPO | Acquired | Acquired | ||
Companies | |||||
Valuation | |||||
Acquirer | Public | ||||
Sources | 5 | 1 | 8 |
SR One Acquisitions
2 Acquisitions
SR One acquired 2 companies. Their latest acquisition was Gryphon Therapeutics on February 25, 1999.
Date | Investment Stage | Companies | Valuation Valuations are submitted by companies, mined from state filings or news, provided by VentureSource, or based on a comparables valuation model. | Total Funding | Note | Sources |
---|---|---|---|---|---|---|
2/25/1999 | Series B | $44.25M | Acquired | |||
10/2/1996 | Private Equity |
Date | 2/25/1999 | 10/2/1996 |
---|---|---|
Investment Stage | Series B | Private Equity |
Companies | ||
Valuation | ||
Total Funding | $44.25M | |
Note | Acquired | |
Sources |
SR One Fund History
8 Fund Histories
SR One has 8 funds, including SR One Fund II.
Closing Date | Fund | Fund Type | Status | Amount | Sources |
---|---|---|---|---|---|
3/27/2023 | SR One Fund II | $600M | 2 | ||
11/19/2020 | SR One Fund I | ||||
8/9/2013 | Action Potential Venture Capital Fund | ||||
1/1/1985 | S.R. One Ltd. | ||||
SR One Capital Fund I-A |
Closing Date | 3/27/2023 | 11/19/2020 | 8/9/2013 | 1/1/1985 | |
---|---|---|---|---|---|
Fund | SR One Fund II | SR One Fund I | Action Potential Venture Capital Fund | S.R. One Ltd. | SR One Capital Fund I-A |
Fund Type | |||||
Status | |||||
Amount | $600M | ||||
Sources | 2 |
SR One Team
11 Team Members
SR One has 11 team members, including current Chief Executive Officer, Simeon J. George.
Name | Work History | Title | Status |
---|---|---|---|
Simeon J. George | Chief Executive Officer | Current | |
Name | Simeon J. George | ||||
---|---|---|---|---|---|
Work History | |||||
Title | Chief Executive Officer | ||||
Status | Current |
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