Predict your next investment

See what CB Insights has to offer

About Protein Design Labs

Protein Design Labs Headquarter Location

Predict your next investment

The CB Insights tech market intelligence platform analyzes millions of data points on venture capital, startups, patents , partnerships and news mentions to help you see tomorrow's opportunities, today.

Latest Protein Design Labs News

Protein Design Labs, Progenics to Collaborate on Humanization of HIV Antibody

Jun 11, 2017

Protein Design Labs Inc. (PDL; Mountain View, CA) and Progenics Pharmaceuticals Inc. (Tarrytown, NY) have signed an agreement for the humanization by PDL of PRO 140, Progenics' novel anti-CCR5 monoclonal antibody that potently blocks HIV replication in the laboratory. Under the agreement, Progenics will pay PDL a licensing and signing fee, will make additional payments upon the achievement of certain milestones, and will pay royalties upon any sales of the antibody. The financial terms of the agreement were not disclosed. According to Paul Maddon, chairman and CEO of Progenics, their objective in working with PDL is to develop an antibody that retains PRO 140's antiviral activity, but that is more suitable for chronic use in humans. The companies are working to begin clinical testing with PRO 140 next year. PRO 140 is the most potent of six HIV inhibitory monoclonal antibodies against CCR5 isolated by Progenics scientists using Progenics' ProSys technology. PRO 140 blocks the fusion of viral and target cell membranes, an early step of the HIV replication cycle. PRO 140 effectively inhibits HIV entry at concentrations that have no apparent effect on the normal function of CCR5, which mediates the activation and trafficking of immune system cells. Progenics Pharmaceuticals, Inc. is a biopharmaceutical company focusing on the development and commercialization of products for the treatment and prevention of cancer and viral diseases. Protein Design Labs develops humanized antibodies to prevent or treat various disease conditions. For more information: Cary Queen, VP of Research, Protein Design Labs Inc., 2375 Garcia Ave., Mountain View, CA 94043. Tel: 650-903-3700. Fax: 650-903-3730. Like what you are reading? Sign up for our free newsletter SIGN ME UP By clicking Sign Me Up, you agree to our Terms and that you have read our Privacy Policy .

Protein Design Labs Acquisitions

1 Acquisition

Protein Design Labs acquired 1 company. Their latest acquisition was Angiomics on August 02, 2004.

Date

Investment Stage

Companies

Valuation
Valuations are submitted by companies, mined from state filings or news, provided by VentureSource, or based on a comparables valuation model.

Total Funding

Note

Sources

8/2/2004

$99M

Acquired

Date

8/2/2004

Investment Stage

Companies

Valuation

$99M

Total Funding

Note

Acquired

Sources

CB Insights uses Cookies

CBI websites generally use certain cookies to enable better interactions with our sites and services. Use of these cookies, which may be stored on your device, permits us to improve and customize your experience. You can read more about your cookie choices at our privacy policy here. By continuing to use this site you are consenting to these choices.