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Venture Capital
pci.upenn.edu

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Investments

25

Partners & Customers

4

About PCI Ventures

PCI Ventures (PCIV) at the University of Pennsylvania is dedicated to supporting technology commercialization within the Penn community. Since 2010, PCIV has worked with over 200 faculty and staff members to form and launch new companies based on selected inventions and innovative technologies.

Headquarters Location

3600 Civic Center Boulevard 9th Floor

Philadelphia, Pennsylvania, 19104,

United States

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Latest PCI Ventures News

Pinpoint Therapeutics secures funds for developing autophagy inhibitors for cancer

Feb 13, 2020

Pinpoint Therapeutics, a US biopharma company focused on developing autophagy inhibitors for cancer treatment, has secured $1 million in debt financing led by California-based venture capital firm Kairos Ventures. The preclinical stage company was founded in 2018 through PCI Ventures, a division of the Penn Center for Innovation (PCI) at the University of Pennsylvania. It was founded by researchers Ravi K. Amaravadi and Jeffrey D. Winkler from the University of Pennsylvania’s Abramson Cancer Center and the Department of Chemistry. Jim Demetriades – founder and Managing Partner of Kairos Ventures said: “Pinpoint has developed best-in-class compounds with unprecedented therapeutic potential and we are thrilled to support their efforts as they develop these novel drug-candidates for treatment of colon cancer, pancreatic cancer, melanoma , and other major unmet needs in oncology.” According to Pinpoint Therapeutics, autophagy is a well-established mechanism of cancer cell survival and drug resistance. The biopharma company claimed that its compounds target a recently discovered enzyme in the autophagy pathway called PPT1, which is expressed highly across most cancers. Pinpoint Therapeutics believes that these inhibitors could be applied to a wide range of cancers alone or in combination with other treatments to overcome the challenge of therapy resistance. The pharma start-up will develop autophagy inhibitors into clinical drugs for evaluating in a variety of treatment-refractory cancers . Christian Peters – CEO of Pinpoint Therapeutics said: “This initial round of financing will allow us to develop a new approach to drugging autophagy, which until now seemed difficult to target in cancer. The activity of PPT1 inhibitors in cancer models has not been seen before in the autophagy space.” Related posts

PCI Ventures Investments

25 Investments

PCI Ventures has made 25 investments. Their latest investment was in EnaChip as part of their Seed VC on September 9, 2021.

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PCI Ventures Investments Activity

investments chart

Date

Round

Company

Amount

New?

Co-Investors

Sources

9/2/2021

Seed VC

EnaChip

$7.1M

Yes

1

8/24/2021

Series B - IV

Linnaeus Therapeutics

$4.34M

No

1

9/1/2019

Incubator/Accelerator

Cartio Therapeutics

Yes

1

2/11/2019

Series B

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$99M

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10

9/7/2018

Series A

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$99M

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10

Date

9/2/2021

8/24/2021

9/1/2019

2/11/2019

9/7/2018

Round

Seed VC

Series B - IV

Incubator/Accelerator

Series B

Series A

Company

EnaChip

Linnaeus Therapeutics

Cartio Therapeutics

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Amount

$7.1M

$4.34M

$99M

$99M

New?

Yes

No

Yes

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Co-Investors

Sources

1

1

1

10

10

PCI Ventures Partners & Customers

4 Partners and customers

PCI Ventures has 4 strategic partners and customers. PCI Ventures recently partnered with coree on November 11, 2021.

Date

Type

Business Partner

Country

News Snippet

Sources

11/18/2021

Partner

COREE partners with Infini Fluidics to develop new mRNA vaccine-making method

Hanmi Science Consortium Science CEO Lim Jong-yoon and Infini Fluidics CEO Sagar Yadavali hold their cooperation agreement at the University of Pennsylvania on Monday .

1

11/18/2021

Partner

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10

9/17/2014

Partner

United States

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10

9/17/2014

Partner

United States

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10

Date

11/18/2021

11/18/2021

9/17/2014

9/17/2014

Type

Partner

Partner

Partner

Partner

Business Partner

Country

United States

United States

News Snippet

COREE partners with Infini Fluidics to develop new mRNA vaccine-making method

Hanmi Science Consortium Science CEO Lim Jong-yoon and Infini Fluidics CEO Sagar Yadavali hold their cooperation agreement at the University of Pennsylvania on Monday .

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Sources

1

10

10

10

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