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Government
nhmrc.gov.au

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Investments

1

Partners & Customers

1

About National Health and Medical Research Council

National Health and Medical Research Council provides grants and other funding.

National Health and Medical Research Council Headquarter Location

16 Marcus Clarke St

Canberra, Australian Capital Territory, 2601,

Australia

+61 2 6217 9000

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Latest National Health and Medical Research Council News

Prebiotics may reduce gastrointestinal symptoms among kidney transplant recipients

Mar 21, 2022

Disclosures: Chan reports support from the Australian National Health and Medical Research Council (NHMRC) Postgraduate Scholarship, the Microba recipient grant, the Metro South Research Support Scheme, the Royal Australasian College of Physicians NHMRC Research Excellence top-up award and the Sir Gustav Nossal NHMRC Postgraduate Scholarship award. ADD TOPIC TO EMAIL ALERTS Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . Please try again later. If you continue to have this issue please contact customerservice@slackinc.com . Back to Healio Researchers report it is feasible to recruit and retain acute kidney transplant recipients in trials examining prebiotics on infections and gastrointestinal symptoms, according to data published in the Journal of Renal Nutrition. Further, they found prebiotics may improve gastrointestinal symptoms among kidney transplant recipients. “We wanted to undertake an interventional study to address the gastrointestinal burden and high levels of infections in kidney transplant recipients. In a prior study, we found that approximately 80% of our kidney transplant recipients report gastrointestinal symptoms daily. We also found that the gastrointestinal microbiota is altered as a result of transplantation,” Samuel Chan, MBBS, FRACP, PhD, a consultant nephrologist at the University of Queensland in Australia, told Healio. “Thus, we wanted to see if nutritional therapy (eg, prebiotics) could reduce the gastrointestinal burden and infections in kidney transplant recipients.” In a double-blind, placebo-controlled, randomized trial, Chan and colleagues randomized 56 acute kidney transplant recipients to receive prebiotics in the form of green banana resistant starch (n=27) or placebo in the form of waxy maize (n=29) for 7 weeks. All patients in the feasibility study received a kidney transplant at the same center and were at least 18 years of age. For the first 2 weeks after enrollment, patients consumed 7.5 grams of the treatment daily, then increased to 15 grams daily for the final 5 weeks. During a median follow-up of 1.8 months, 19 patients experienced 22 infectious events. Similarly, 22% of the intervention group were hospitalized and experienced gastrointestinal and skin adverse events, whereas 21% of the control group were hospitalized and experienced cardiovascular, gastrointestinal and skin adverse events. Patients from both groups experienced similar adherence, tolerability and infection events. “We found that prebiotics may reduce gastrointestinal symptoms in acute kidney transplant recipients. Our study was small, so it was difficult to make sensible comments about the infections. With more research, we are hoping to let our patients know the results of our study and that infections and gastrointestinal burden may be reduced as a consequence of prebiotic supplementation,” Chan told Healio. “We want to extend our study to undertake a multicenter randomized controlled study of prebiotics [vs.] placebo to look at gastrointestinal burden and infection outcomes.” Read more about

National Health and Medical Research Council Investments

1 Investments

National Health and Medical Research Council has made 1 investments. Their latest investment was in University of Melbourne as part of their Grant on July 7, 2020.

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National Health and Medical Research Council Investments Activity

investments chart

Date

Round

Company

Amount

New?

Co-Investors

Sources

7/23/2020

Grant

University of Melbourne

$1.07M

Yes

1

Date

7/23/2020

Round

Grant

Company

University of Melbourne

Amount

$1.07M

New?

Yes

Co-Investors

Sources

1

National Health and Medical Research Council Partners & Customers

1 Partners and customers

National Health and Medical Research Council has 1 strategic partners and customers. National Health and Medical Research Council recently partnered with Wellcome Trust on May 5, 2002.

Date

Type

Business Partner

Country

News Snippet

Sources

5/27/2002

Partner

United Kingdom

New Health Programme for S & SE Asia and the Pacific

A major new programme focusing on the health problems of developing countries in South and South-east Asia and the Pacific is being launched by the Wellcome Trust in partnership with the National Health and Medical Research Council of Australia ; the Ministry of Research , Science and Technology ; and the Health Research Council of New Zealand .

1

Date

5/27/2002

Type

Partner

Business Partner

Country

United Kingdom

News Snippet

New Health Programme for S & SE Asia and the Pacific

A major new programme focusing on the health problems of developing countries in South and South-east Asia and the Pacific is being launched by the Wellcome Trust in partnership with the National Health and Medical Research Council of Australia ; the Ministry of Research , Science and Technology ; and the Health Research Council of New Zealand .

Sources

1

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