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Academic/University
kuleuven.be

Investments

19

Portfolio Exits

12

Partners & Customers

10

About KU Leuven

KU Leuven is a research and educational institution with an international reputation. All courses at this university are based on the innovative research of its scientists and professors.

Headquarters Location

Leuven,

Belgium

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Latest KU Leuven News

Gout increases the risk of a broad range of cardiovascular diseases

Feb 20, 2024

Gout is associated with an increased risk of a broad range of cardiovascular diseases, according to new research which looked at the health records of more than 860,000 people. The study, which is published in The Lancet Rheumatology and led jointly by researchers from the Universities of Oxford, Glasgow, and KU Leuven, reveals that having gout is linked with a 58% higher risk of cardiovascular disease, with even higher relative risks noted for females and those under the age 45 who have the condition. Gout, an extremely painful condition that causes swelling and redness in joints, is one of the most common types of inflammatory arthritis in the world. It is more common in men and older individuals, but can impact women and younger people too, and is caused by a build-up of uric acid in the body leading to tiny crystals forming around joints. Previous studies have linked gout to cardiovascular disease risk, but this is the first time researchers have looked at a broad range of diseases impacted in such a large-scale study. To carry out the work the team of UK and European researchers used electronic health records from the Clinical Practice Datalink, and analysed the data from more than 152,000 individuals with gout alongside more than 700,000 matched population controls. The results show that people with gout had an overall higher risk of cardiovascular disease than those without the condition. In particular, women with gout had a 88% higher relative risk of cardiovascular disease compared to women without gout; for men with gout, the risk of cardiovascular disease was 49% higher compared to those without gout. Although the absolute risk of cardiovascular disease increases with age, this study shows that gout appears to amplify this risk to a greater extent in younger individuals (aged <45 years) than older individuals, such that a young person with gout has more than twice the risk of cardiovascular disease than a similarly aged person without gout. This increased risk was seen across all 12 cardiovascular diseases studied in the research, including heart failure, ischaemic heart disease, arrythmias, valve diseases, and venous thromboembolism. In addition, patients with gout had a higher BMI than matched controls, and a notably higher prevalence of other health conditions, including chronic kidney disease and high blood pressure. Researchers say these new findings suggest that identifying and implementing strategies to reduce cardiovascular risk in people with gout should now be a priority, for both further research and clinical practice. Lead senior author of the paper Dr Nathalie Conrad, based at the KU Leuven in Belgium, and an Honorary Research Fellow at the Nuffield Department of Women’s & Reproductive Health at the University of Oxford, and the University of Glasgow, said: 'The present results complement a now large body of evidence of substantial cardiovascular risks associated with gout, as well as other immune­mediated inflammatory conditions. To date, these conditions are less commonly considered in cardiovascular disease prevention guidelines and risk scores, nor are there specific prevention measures for these patients. These data suggest this might need to change, and the clinical community may need to consider cardiovascular disease screening and prevention as an integral part of the management of gout.' First author of the paper Dr Lyn D Ferguson, Consultant and Honorary Senior Clinical Lecturer based at the University of Glasgow, said: 'This work highlights the importance of screening for and managing a range of cardiovascular diseases in people with gout. Gout could be considered a metabolic condition and management should include addressing the heart and body weight alongside joints.'

KU Leuven Investments

19 Investments

KU Leuven has made 19 investments. Their latest investment was in Rewind Therapeutics as part of their Series B on January 25, 2023.

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KU Leuven Investments Activity

investments chart

Date

Round

Company

Amount

New?

Co-Investors

Sources

1/25/2023

Series B

Rewind Therapeutics

No

6

8/31/2022

Seed VC

Aspect Analytics

$1.8M

Yes

1

8/25/2022

Seed VC

AstriVax

$29.9M

Yes

3

5/12/2022

Series C

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$99M

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10

11/2/2021

Seed VC

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$99M

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10

Date

1/25/2023

8/31/2022

8/25/2022

5/12/2022

11/2/2021

Round

Series B

Seed VC

Seed VC

Series C

Seed VC

Company

Rewind Therapeutics

Aspect Analytics

AstriVax

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Amount

$1.8M

$29.9M

$99M

$99M

New?

No

Yes

Yes

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Co-Investors

Sources

6

1

3

10

10

KU Leuven Portfolio Exits

12 Portfolio Exits

KU Leuven has 12 portfolio exits. Their latest portfolio exit was nextAuth on October 24, 2023.

Date

Exit

Companies

Valuation
Valuations are submitted by companies, mined from state filings or news, provided by VentureSource, or based on a comparables valuation model.

Acquirer

Sources

10/24/2023

Acquired

$99M

4

1/1/2023

Spinoff / Spinout

Obulytix

$99M

1

8/31/2022

Acq - Fin

$99M

3

1/1/2022

Spinoff / Spinout

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$99M

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10

1/1/2019

Spinoff / Spinout

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$99M

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10

Date

10/24/2023

1/1/2023

8/31/2022

1/1/2022

1/1/2019

Exit

Acquired

Spinoff / Spinout

Acq - Fin

Spinoff / Spinout

Spinoff / Spinout

Companies

Obulytix

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Valuation

$99M

$99M

$99M

$99M

$99M

Acquirer

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Sources

4

1

3

10

10

KU Leuven Partners & Customers

10 Partners and customers

KU Leuven has 10 strategic partners and customers. KU Leuven recently partnered with University of Melbourne on October 10, 2023.

Date

Type

Business Partner

Country

News Snippet

Sources

10/26/2023

Partner

Australia

KU Leuven and University of Melbourne extend collaboration with extra investment of €10 million and 20 new research projects

KU Leuven and the University of Melbourne have signed a new agreement during the Belgian Economic Mission in Australia which will further deepen their existing research collaboration .

1

6/6/2023

Partner

Senegal

1

1/16/2023

Partner

Belgium, and Norway

CEPI, Belgian universities to partner to enhance global pandemic preparedness – CEPI

Oslo , Norway , Leuven and Antwerp , Belgium , 16 January , 2023 : CEPI , the Coalition for Epidemic Preparedness Innovations , has entered into strategic partnerships with the Belgian Universities KU Leuven and the University of Antwerp .

1

4/5/2022

Partner

Belgium

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10

3/14/2022

Partner

Finland

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10

Date

10/26/2023

6/6/2023

1/16/2023

4/5/2022

3/14/2022

Type

Partner

Partner

Partner

Partner

Partner

Business Partner

Country

Australia

Senegal

Belgium, and Norway

Belgium

Finland

News Snippet

KU Leuven and University of Melbourne extend collaboration with extra investment of €10 million and 20 new research projects

KU Leuven and the University of Melbourne have signed a new agreement during the Belgian Economic Mission in Australia which will further deepen their existing research collaboration .

CEPI, Belgian universities to partner to enhance global pandemic preparedness – CEPI

Oslo , Norway , Leuven and Antwerp , Belgium , 16 January , 2023 : CEPI , the Coalition for Epidemic Preparedness Innovations , has entered into strategic partnerships with the Belgian Universities KU Leuven and the University of Antwerp .

Subscribe to see more

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Sources

1

1

1

10

10

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