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Public-Private Partnership
sep.benfranklin.org

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Investments

349

Portfolio Exits

55

Funds

6

Partners & Customers

5

Service Providers

2

About Ben Franklin Technology Partners of Southeastern PA

Ben Franklin Technology Partners combines the best practices of early stage investing with a higher purpose – to lead the region's technology community to new heights, creating jobs and transforming lives. For over 30 years, Ben has been the leading seed stage capital provider for the region's technology sectors, investing over $175 million in more than 1,750 regional technology companies, many of which have gone on to become industry leaders. Ben Franklin has also launched university/industry partnerships that accelerate scientific discoveries to commercialization, and has seeded regional initiatives that strengthen our entrepreneurial community.

Headquarters Location

Building 100 Innovation Center 4801 S. Broad Street, Suite 200

Philadelphia, Pennsylvania, 19112,

United States

215-972-6700

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Latest Ben Franklin Technology Partners of Southeastern PA News

QR Pharma Receives Seed Investment from Ben Franklin Technology Partners for Further Development of Clinical Stage Compounds to Treat Alzheimer’s Disease

Mar 29, 2018

Radnor, PA, April 6, 2009 QR Pharma, Inc., a newly formed specialty pharmaceutical company focused on developing novel therapeutics for the treatment of Alzheimer’s disease, received a $500,000 investment from Ben Franklin Technology Partners of Southeastern PA. The investment will further the clinical development of two lines of compounds, Posiphen® and bisnorcymserine and their respective analogs to treat Alzheimer’s disease (AD) and cognitive impairment. QR Pharma was founded to capitalize on technology that was invented by Dr. Nigel Greig at NIA/NIH, QR Pharma obtained an exclusive worldwide license in November 2008. “The technology targets two critical pathways in the treatment of Alzheimer’s disease and achieves both in a manner that has the potential to impact disease progression and provide symptomatic relief,” said Maria Maccecchini, Ph.D., CEO of QR Pharma and a successful biotechnology veteran in the region. “In the last 6 months we have assembled a world-class team experienced in the strategic development of Alzheimer’s drugs. We are focused on aggressively moving this new technology forward in the clinic to show efficacy in mild as well as severe Alzheimer’s cases.” Alzheimer’s disease is a debilitating condition that accounts for 64% of all dementias, and afflicts more than 30 million people worldwide. Its economic burden and impact on patient wellness and quality of life for both patients and their caregivers are devastating. In the US alone, the estimated direct and indirect annual cost of patient care is over $100 billion. Current Alzheimer’s drugs provide symptomatic relief with limited levels of success, and fail to prevent the progression of the underlying disease. Today, the greatest unmet need is the availability of disease-modifying therapies. Thought leaders believe that targeting the accumulation of amyloid-ß peptide (Aß) that forms into hallmark plaques in the brain will change the course of Alzheimer’s. However, a second hypothesis states that amyloid precursor protein (APP) is instrumental in inducing neuronal cell death before it is processed into Aß. QR’s lead compound, Posiphen®, inhibits APP synthesis in preclinical models and, thereby, reduces A? accumulation into plaque as well as APP induced nerve cell death. Posiphen® is distinct from the Alzheimer’s drugs currently available or in clinical development, because it has a dual mechanism of action: it reduces APP/Aß generation through direct inhibition of APP synthesis, and it may provide symptomatic relief through acetylcholinesterase inhibition (AChEI). Posiphen® was tested in single and multiple ascending dose phase I trials, and found to be safe. The next compound in QR’s pipeline is a preclinical stage compound, bisnorcymserine (BNC). BNC is a centrally active, reversible butyrylcholinesterase inhibitor, and is expected to work in advanced Alzheimer’s, at a stage when little AChE remains in the brain and BChE predominates. Like Posiphen®, BNC has been shown to reduce the generation of APP/Aß in the brain in preclinical models, by lowering the rate of synthesis of APP. “I look forward to further development of these experimental Alzheimer’s drugs,” Dr. Greig noted. “With the aging of our population, it is more critical than ever that we find ways to slow the progression of the disease, or prevent it altogether.” About QR Pharma, Inc About QR Pharma, Inc.: Headquartered in Radnor, Pennsylvania, QR Pharma, Inc. is a clinical-stage specialty pharmaceutical company committed to developing therapeutics with novel approaches for the treatment of cognitive impairment and Alzheimer’s disease (AD). QR currently has two product development programs based on oral small-molecule, blood-brain barrier passable therapeutics that target two distinct pathways for the treatment of AD. Contact: Maria L. Maccecchini, PhD Tel: 484 253 2296

Ben Franklin Technology Partners of Southeastern PA Investments

349 Investments

Ben Franklin Technology Partners of Southeastern PA has made 349 investments. Their latest investment was in Avisi Technologies as part of their Grant - III on August 8, 2022.

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Ben Franklin Technology Partners of Southeastern PA Investments Activity

investments chart

Date

Round

Company

Amount

New?

Co-Investors

Sources

8/12/2022

Grant - III

Avisi Technologies

Yes

1

8/12/2022

Grant

ERPHealth

Yes

1

8/12/2022

Grant

Innovative Supply Solutions

Yes

1

3/17/2022

Seed

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$99M

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10

9/22/2021

Series A - III

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$99M

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10

Date

8/12/2022

8/12/2022

8/12/2022

3/17/2022

9/22/2021

Round

Grant - III

Grant

Grant

Seed

Series A - III

Company

Avisi Technologies

ERPHealth

Innovative Supply Solutions

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Amount

$99M

$99M

New?

Yes

Yes

Yes

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Co-Investors

Sources

1

1

1

10

10

Ben Franklin Technology Partners of Southeastern PA Portfolio Exits

55 Portfolio Exits

Ben Franklin Technology Partners of Southeastern PA has 55 portfolio exits. Their latest portfolio exit was Atrin Pharmaceuticals on May 16, 2022.

Date

Exit

Companies

Valuation
Valuations are submitted by companies, mined from state filings or news, provided by VentureSource, or based on a comparables valuation model.

Acquirer

Sources

5/16/2022

Acquired

$99M

2

5/5/2022

Acquired

$99M

2

1/26/2022

Acquired

$99M

1

1/17/2022

Acquired

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$99M

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10

12/20/2021

Acquired

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$99M

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10

Date

5/16/2022

5/5/2022

1/26/2022

1/17/2022

12/20/2021

Exit

Acquired

Acquired

Acquired

Acquired

Acquired

Companies

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Valuation

$99M

$99M

$99M

$99M

$99M

Acquirer

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Sources

2

2

1

10

10

Ben Franklin Technology Partners of Southeastern PA Fund History

6 Fund Histories

Ben Franklin Technology Partners of Southeastern PA has 6 funds, including Global Opportunity Philadelphia Fund.

Closing Date

Fund

Fund Type

Status

Amount

Sources

2/7/2019

Global Opportunity Philadelphia Fund

Early-Stage Venture Capital

Open

$15M

1

2/7/2019

Global Opportunity Philadelphia Fund I

$99M

10

4/17/2018

Venture Chesco

$99M

10

3/21/2007

Gap Fund

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$99M

10

Drexel and Ben Franklin Seed Fund

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10

Closing Date

2/7/2019

2/7/2019

4/17/2018

3/21/2007

Fund

Global Opportunity Philadelphia Fund

Global Opportunity Philadelphia Fund I

Venture Chesco

Gap Fund

Drexel and Ben Franklin Seed Fund

Fund Type

Early-Stage Venture Capital

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Status

Open

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Amount

$15M

$99M

$99M

$99M

Sources

1

10

10

10

10

Ben Franklin Technology Partners of Southeastern PA Partners & Customers

5 Partners and customers

Ben Franklin Technology Partners of Southeastern PA has 5 strategic partners and customers. Ben Franklin Technology Partners of Southeastern PA recently partnered with Miramar Global on September 9, 2019.

Date

Type

Business Partner

Country

News Snippet

Sources

9/28/2019

Vendor

United Kingdom

Transforming Human Performance In The Age of The Connected Enterprise. Ben Franklin Technology Partners Retains Global Technology Executive Search Firm - Ben Franklin Technology Partners

PHILADELPHIA , Pa. -- John Hodge , Managing Partner of Miramar Global , North America , announces that his firm is now the premier Circle of BENefits executive search partner for Ben Franklin .

1

6/25/2019

Partner

United States

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10

4/27/2018

Partner

United States

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10

5/27/2016

Partner

United States

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10

7/7/2011

Partner

United States

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10

Date

9/28/2019

6/25/2019

4/27/2018

5/27/2016

7/7/2011

Type

Vendor

Partner

Partner

Partner

Partner

Business Partner

Country

United Kingdom

United States

United States

United States

United States

News Snippet

Transforming Human Performance In The Age of The Connected Enterprise. Ben Franklin Technology Partners Retains Global Technology Executive Search Firm - Ben Franklin Technology Partners

PHILADELPHIA , Pa. -- John Hodge , Managing Partner of Miramar Global , North America , announces that his firm is now the premier Circle of BENefits executive search partner for Ben Franklin .

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Sources

1

10

10

10

10

Ben Franklin Technology Partners of Southeastern PA Service Providers

2 Service Providers

Ben Franklin Technology Partners of Southeastern PA has 2 service provider relationships

Service Provider

Associated Rounds

Provider Type

Service Type

Counsel

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Service Provider

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Associated Rounds

Provider Type

Counsel

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Service Type

Partnership data by VentureSource

Ben Franklin Technology Partners of Southeastern PA Team

5 Team Members

Ben Franklin Technology Partners of Southeastern PA has 5 team members, including current Chief Executive Officer, President, Scott Nissenbaum.

Name

Work History

Title

Status

Scott Nissenbaum

Chief Executive Officer, President

Current

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Name

Scott Nissenbaum

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Work History

Title

Chief Executive Officer, President

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Status

Current

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