Predict your next investment

Tryton Medical company logo
HEALTHCARE | Medical Devices & Equipment / Surgical Devices
trytonmedical.com

See what CB Insights has to offer

Founded Year

2003

Stage

Series G | Alive

Total Raised

$87M

Last Raised

$4M | 5 yrs ago

About Tryton Medical

Tryton Medical is a developer of stent systems for the treatment of bifurcation lesions. The Tryton Side Branch Stent System is built for bifurcation using Tri-ZONE technology to offer a dedicated strategy for treating bifurcation lesions. Tryton's cobalt chromium stent is deployed in the side branch artery using a standard single-wire balloon-expandable stent delivery system. A conventional drug-eluting stent is then placed in the main vessel. The stent system has received CE Mark and is commercially available throughout Europe, Russia and the Middle East. It is approved in the United States for investigational use only.

Tryton Medical Headquarter Location

1000 Park Forty Plaza Suite 325

Durham, North Carolina, 27713,

United States

919-226-1490

Latest Tryton Medical News

Elcam Medical Joins Serenno Medical as Strategic Investor and Manufacturer of its Automatic Monitoring of Kidney Function Device

Jan 20, 2021

January 20, 2021 Serenno Medical , developer of medical devices for patient monitoring in a hospital setting, announced today that Elcam Medical , a leading producer of medical devices, has invested  $1.5 million in the Company and will also manufacture SentinelTM, Serenno’s urine output and intra-abdominal pressure digital monitoring device for the detection of acute kidney injury (AKI). Elcam Medical join existing investors Alon Medtech and serial medical device inventor, entrepreneur and investor, Dr. Shimon Eckhouse. The partnership announced today combines Serenno’s unique solution with Elcam’s superior manufacturing experience to deliver high quality products at a competitive price, that will enable the use of Sentinel in a variety of hospital environments. Continuous kidney function assessment allows the early detection of AKI, a common condition in hospitalized patients that significantly increases risk of mortality during and after hospitalization. Accurate measurement of urine output (UO) is clinically accepted as the best method for monitoring changes in kidney function. However, UO is currently monitored intermittently and manually by ICU staff, therefore acute changes in urine flow are difficult to detect. Thus, kidney injury is often detected relatively late, sometimes after it is impossible to prevent further progression. Beyond the high death toll associated with kidney failure routinely in the ICU, the recent spread of COVID19 had greatly increased prevalence of, and death from AKI, while vastly increasing the demand and exposure risk on medical professionals and ICUs worldwide. Sentinel offers a simple and cost-effective solution for the precise, continuous measurement of urine volume and flow rate in real time. The system promotes early detection of kidney injury, while there is still time to intervene and prevent further damage. It aims to automatically and accurately detect small changes in kidney function, allowing remote detection by the medical staff, thus reducing both patient and caregiver risk. “The investment by Elcam Medical is a strong endorsement, and will allow us to swiftly move toward commercialization of our device,” said Tomer Lark, Serenno’s co-founder and CEO. “Elcam’s world class production capabilities and experience, will enable mass production and increased market access of Sentinel. Our plan is to begin deployment of the devices in several US hospitals towards the end of 2021, in the hope to eventually reduce kidney failure risk for every patient at ICUs.” Dr. Shimon Eckhouse, Serenno’s Chairman, added, “We are pleased with Elcam’s investment, which marks the first commitment in Serenno’s larger planned current financial round. This partnership with Elcam is an excellent indication of the high degree of innovation and the significance of Serenno’s solution for the advancement of monitoring technologies. We are confident that Elcam’s leadership position in the global point-of-care market will play a critical role in bringing Serenno’s exciting technology to ICUs and patients around the world.” “Our investment in Serenno and the establishment of a production line for its device is aligned with Elcam’s strategy to cooperate with promising Israeli startups to deliver products with added value for the patient,” said Igal Kohn, Elcam Medical’s CEO. “Elcam Medical has joined Serenno as a board member and we look forward to taking part in the Company’s continued successes.” The total coronary stent market comprises bare-metal stents, drug-eluting stents, covered stents, and bifurcated stents. Stents can be defined as small mesh tubes inserted into an artery to prevent it from collapsing and keep it open after an angioplasty surgery (percutaneous coronary intervention, or PCI). Following multiple clinical studies that presented evidence of over-stenting in the U.S market, the value of the overall market has decreased through 2019 and is expected to trend downwards over the coming years, outside of COVID-19-related fluctuations. We have identified the different types of stents and analyzed their benefits and draw-backs: Top Companies for Coronary Stents by Market Share 1. Boston Scientific – The leading competitor in the coronary stent market was Boston Scientific. Most of the company’s success can be attributed to its strong position in the drug-eluting stents (DES) market, where it held the leading share. The company currently offers the SYNERGY™ and REBEL™ BMS product line. SYNERGY™ is the first and only FDA-approved DES with abluminal bioabsorbable polymer coating available in the U.S. coronary stent market. REBEL™ is made of a platinum chromium alloy, which is designed to reduce device usage, procedure times, and radiation exposure. 2. Medtronic – Medtronic is the second-leading competitor and maintained a notable position in both the bare-metal stents (BMS) and drug-eluting stents (DES) markets. Through strategic acquisitions and aggressive bundling, Medtronic has increased its share across the interventional cardiology market in recent years. The company currently offers the Resolute Onyx™ and Resolute Integrity™ DES product lines, as well as the Integrity™ BMS product line. Unlike Boston Scientific and Abbott’s DES devices, which use the everolimus drug, Medtronic’s DES devices use zotarolimus. 3. Abbott  – Abbott is the third-leading competitor in the coronary stent market. Competition between Abbott and Medtronic has increased within the DES market, resulting in Abbott losing share in recent years. The company currently offers the XIENCE™ and Multi-Link Vision™ product lines. Multi-Link Vision™ has been the leading BMS in the U.S. since its introduction. It is constructed of a cobalt-chromium alloy that is more radiopaque than stainless steel stents. This alloy is also stronger than stainless steel, which allows stent construction to be much thinner while still retaining its strength. Coronary Stent Market Trends – By Type 1. Drug-eluting stents (DES) – All stents have a risk that scar tissue will form and narrow the artery again. This scar tissue can block blood flow. However, drug-eluting stents are coated with drugs that prevent scar tissue from growing into the artery. DES are used for an overwhelming majority of stenting procedures, due to the continued publication of clinical studies supporting their safety and efficacy as the gold standard for stenting procedures. With this clinical backing, the DES market sits at over $1 billion. However, due to increased bundling and competitive pricing, significant ASP depreciation resulted in negative market value growth in 2019 . Negative to flat growth is expected to continue for most of the next few years. 2. Bare-metal stents (BMS) – “Bare-metal stents are mesh-like tubes of thin wire without a coating or covering. Ideally, bare-metal stents will be covered by a new layer of endothelial cells, sealing it into the vessel wall, within a few weeks after implant.” – DAIC . Bare-metal stents were once the gold-standard choice for stenting procedures but have lost substantial share to drug-eluting stents. It is expected that the segment will continue to contract in market value in the upcoming years with decline rates in the double-digits. 3. Covered stents – Covered stents are composed of fabric or graft material, such as polytetrafluoroethylene (PTFE), covering a metal stent. These devices are seldom used and are indicated for the treatment of free perforations of native coronary arteries or saphenous vein grafts, which would have been treated with a coronary artery bypass graft (CABG) procedure in the past. The incidence rate of coronary perforation has historically been low. It is estimated to occur in less than 1% of percutaneous coronary intervention (PCI) procedures performed in the United States. 4. Bifurcated stents – Bifurcated stents represent a small fraction of the total market value. Tryton Medical’s TRYTON® Side Branch was the first dedicated bifurcated stent to be approved in the U.S. market, in March 2017. The segment was once expected to experience very rapid growth, due to the strategic alliance between Tryton and Cardinal Health. However, after the first year on the market, unit sales declined sharply, due to a lack of clinical studies for and efficacy of the stents. Coronary Stent Market Analysis and Forecast Overall, the U.S. Coronary Stent market size was valued at over $1 billion in 2020. This is not expected to increase by much over the next few years, as the market observed a loss of 22% resulting from the impacts of COVID19. This is expected to bounce back with growth over the next 2 years but then drop off again as stents become less used in surgeries. January 19, 2021 Bioclinica, an integrated solutions provider of clinical life science and technology expertise, today announced a new product to support redaction of sensitive patient information from videos, photos, and PDFs in clinical trials. Bioclinica notes the addition of Image Redact AI to the company’s portfolio of specialty software solutions makes it the first and only company that can redact sensitive patient identifiers from videos in addition to photos and PDFs. Historically, it has been very difficult to ensure videos fully comply with patient privacy regulations in clinical trials, increasing the risk of costly penalties, downstream issues, and reputation damage for trial sponsors. With Bioclinica’s new AI application, sponsors benefit from peace of mind as well as processing capabilities that reduce time to redact patient identifiers within videos from days to hours. The launch of Image Redact AI closely follows Bioclinica’s acquisition of Saliency , a Silicon Valley-based AI company with technology capable of dramatic acceleration of image QC and interpretation to support rapid development of digital diagnostics and therapeutics. “Image Redact AI is the latest demonstration of how we are delivering value to our customers using cutting-edge technology,” said Dan Gebow, PhD, Chief Innovation Officer at Bioclinica. “Today, we can include videos in the long list of file types that our image de-identification system can handle with ease.” Bioclinica Image Redact AI safeguards sensitive clinical trial data by automatically redacting sensitive patient identifiers from videos, photos, and PDFs. It is the only solution that pairs a high level of AI-driven de-identification with the human oversight of an experienced quality control team to help ensure videos and photos comply with 21 CFR Part 11, EU GDPR, and other privacy regulations. Research that utilizes video or other image formats for studies on vision loss, gait or other movement analysis, dermatology, dental, or behavioral research are especially prone to issues with current products that blur a patient’s entire face. These solutions do not work for this kind of research where it is necessary to see parts of the face, such as the upper lip, forehead, or skin color. In these instances, a sponsor’s only option was to do the redaction themselves. This manual process is error-prone, time-intensive, and can consume valuable research dollars. Prior to submitting a video, photo, or PDF to our secure, 100% browser-based Global Cloud Network, Image Redact AI pre-screens to ensure accurate file type and size. The technology then performs the de-identification process to remove all sensitive patient information, followed by a 100% human visual quality control review by experienced Bioclinica technicians to ensure proper de-identification before the data is made available.

Predict your next investment

The CB Insights tech market intelligence platform analyzes millions of data points on venture capital, startups, patents , partnerships and news mentions to help you see tomorrow's opportunities, today.

Expert Collections containing Tryton Medical

Expert Collections are analyst-curated lists that highlight the companies you need to know in the most important technology spaces.

Tryton Medical is included in 2 Expert Collections, including Medical Devices.

M

Medical Devices

8,184 items

Companies developing medical devices (per the IMDRF's definition of "medical device"). Includes software, lab-developed tests (LDTs), and combination products. *Columns updated as regularly as possible.

3

3D Printing

411 items

Tryton Medical Patents

Tryton Medical has filed 25 patents.

The 3 most popular patent topics include:

  • Implants (medicine)
  • Prosthetics
  • Vascular diseases
patents chart

Application Date

Grant Date

Title

Related Topics

Status

3/11/2013

12/10/2019

Implants (medicine), Prosthetics, Cardiology, Vascular diseases, Interventional cardiology

Grant

Application Date

3/11/2013

Grant Date

12/10/2019

Title

Related Topics

Implants (medicine), Prosthetics, Cardiology, Vascular diseases, Interventional cardiology

Status

Grant

Tryton Medical Web Traffic

Rank
Page Views per User (PVPU)
Page Views per Million (PVPM)
Reach per Million (RPM)
CBI Logo

Tryton Medical Rank

CB Insights uses Cookies

CBI websites generally use certain cookies to enable better interactions with our sites and services. Use of these cookies, which may be stored on your device, permits us to improve and customize your experience. You can read more about your cookie choices at our privacy policy here. By continuing to use this site you are consenting to these choices.