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sinogene.com.cn

Founded Year

2012

Stage

Series B - III | Alive

Total Raised

$15.63M

Last Raised

$15.63M | 9 mos ago

About SINOGENE

SINOGENE is an animal genetic science company based in China that focuses on gene testing, gene editing, cell therapy, animal cloning, and other services.

SINOGENE Headquarter Location

Building 310, 311, 312, Building 16, No. 37 Chaoqian Road Science and Technology Park, Changping District

Beijing, Beijing,

China

+86 010-89785957

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Expert Collections containing SINOGENE

Expert Collections are analyst-curated lists that highlight the companies you need to know in the most important technology spaces.

SINOGENE is included in 1 Expert Collection, including Regenerative Medicine.

R

Regenerative Medicine

1,818 items

Regenerative medicine refers to the process of activating, replacing, engineering or regenerating human genetic material, cells, tissues or organs to restore normal function. It also includes bioengineered tissues used for in vitro testing (e.g. organ-on-a-chip, organoids).

Latest SINOGENE News

Would you clone your dog or cat? Some Singapore pet owners have taken the first step

Dec 3, 2021

Some Singapore pet owners have taken the first step Pet cloning sounds novel but has been around for over a decade. People in favour of the practice say some pets are ‘one in a million’, but opponents cite animal welfare and other issues. Dr Jean-Paul Ly's dog, Khan, was fearless, intelligent and a big source of comfort. Photo courtesy of Jean-Paul Ly SINGAPORE: Travelling between Sydney and Gold Coast in Australia years ago, vet Jean-Paul Ly and his children stopped at a restaurant for a meal. A farmer walked in with two cattle dog puppies. Ly’s children cuddled the dogs and asked their father if they could have them. The family could take only one, and Ly chose the blue cattle dog. Eight-week-old Khan quickly showed it was fearless and intelligent. On the third day at its new home in Gold Coast, it went missing. The children walked along the nearby river, calling its name. When they returned home, they found it standing by the door, Ly recounted. Khan was also a source of comfort when Ly was at his lowest. “He’d sit there and look at you. And when he’d look at you, it was like he understood,” said Ly. “When I was sad, he’d come up and nuzzle up against me. “When he died, a piece of me died with him.” Seven to eight months before Khan died at the age of 17, Ly took the dog’s skin cells and had the sample frozen. After its death in August, he decided to try cloning Khan at an overseas facility: Sinogene, a Chinese company that made the headlines in 2019 when it produced China’s first cloned cat. The price tag for cloning at the Beijing facility: About US$50,000 (S$68,500). If successful, Khan’s clone might be the first such pet to be imported into Singapore. China's first cloned kitten, Garlic (bottom), being licked by its surrogate mother at the Chinese pet cloning company Sinogene. (Photo: AFP/STR) In countries where pets have already been successfully cloned, the practice has been a matter for debate. Singer Barbra Streisand, for instance, drew a range of reactions in 2018 when she disclosed that two of her dogs were clones of a previous dog called Samantha. Three entities in the world do pet cloning: Besides Sinogene, there is Sooam Biotech in South Korea — where it reportedly costs about US$100,000 to clone a dog — and ViaGen Pets and Equine based in Texas, United States. SOME HAVE STORED PETS’ DNA OVERSEAS In Singapore, some vets have seen clients who want to take skin samples of their pets in case they want to clone them in future. But it is not apparent that any clients have gone ahead with the cloning. ViaGen Pets told CNA Insider that “a few clients in Singapore” have stored DNA with the company, but none of them are pet cloning clients yet. Genetic preservation costs US$1,600 at ViaGen, the company said. It charges US$35,000 to clone a cat, US$50,000 to clone a dog and US$85,000 to clone a horse. Ly, who came out of a five-year retirement last year and practises at Animal Wellness Centre, said he has encountered six such clients in the past eight years. In a recent episode of On The Red Dot, he extracted a skin sample from young English bulldog Wouwou through a process called a punch biopsy. English bulldog Wouwou. “It’s a beautiful patient,” Ly said. “She’s a really nice dog. That’s one of the reasons why the owners want to clone (her). You get one in a million. You get a dog that’s so fantastic.” Wouwou’s owner said on the programme: “Having a dog, it’s like having a child. But then you know that their lifespan isn’t going to outlive yours, in a way. It’s nice to just have that at the back of your mind. Like, oh, I’d have the option to clone her.” WATCH: Pet surgery and cloning? Life of vets | On The Red Dot | At the vets — part 2 (23:24) Cathy Chan, co-founder and director of The Animal Doctors, has seen “a few” pet owners enquiring about obtaining skin samples for this purpose. The multi-vet practice, with two clinics in Ang Mo Kio and Tiong Bahru, received its first enquiry in January, she said. While The Animal Doctors have carried out requests and respect this decision of clients who may wish to clone their pets, “we do advise clients to consider the ethics of doing so”, she added. “We do explain that there are unknowns when dealing with cloning. We also try to keep the perspective that the cloned animal isn’t likely to be the exact same pet they had before, in terms of behaviour and health.” The vet cited ethical and animal welfare implications. “Scientifically, it’s still an unknown, and there isn’t enough evidence to support this practice, especially with respect to the long-term survival and health of these pets,” she said. “These cloning companies are often commercial and give a promise/false hope to an owner who may be grieving (for) their beloved pet. This practice is highly questionable.” The National Parks Board’s Animal and Veterinary Service does not track whether there are cloned pets in Singapore. Its import requirements do not include a declaration of whether a pet is a clone. Ly and fellow vet Lee Yee Lin think it unlikely, however, that any such pets have been imported so far. The Singapore Veterinary Association (SVA), meanwhile, “strongly opposes” the cloning of companion animals. The costs and negative implications for animal welfare far outweigh the benefits, if any, of pet cloning, it said. The SVA said it is “strongly supportive” of scientific advancement and can sympathise with pet owners who may be drawn to the prospect of replacing a former pet via animal cloning. “However, overall, pet cloning doesn’t improve animal welfare, animal health nor does it have any real social value in nurturing the human-animal bond,” it added. The association described the promise of cloning an exact replica of a pet as false because the expression of a pet’s genome “as a whole” is beyond any laboratory’s control. “Just like in humans, the experiences and environment that a pet is raised in shape the overall identity and character of the pet,” it said. The SVA is also against cloning facilities using animals bred for the “sole purpose of harvesting eggs and/or surrogacy”. “As there are likely to be failures including the destruction of numerous embryos, miscarriages and foetal abnormalities developing, the process is repeated as required until an ‘acceptable animal’ is produced,” it said. Overall, the production of clones for commercial purposes doesn’t justify the … suffering of the donor animals.” Thousands of dogs, cats and other animals in Singapore need a home, and pet cloning may “worsen the management of the animal population as a whole, especially if this adversely affects shelter adoption rates”, the SVA noted. HOW A PET IS CLONED In the case of dogs, eggs are taken from a female dog. The nucleus is removed from the donor egg, which is then injected with the nucleus of a body cell of the dog that is to be cloned. Electrical stimulation “activates” the fused cell and it starts to divide. This process is called somatic cell nuclear transfer. The embryo is then implanted into a surrogate mother dog. It takes about 60 days for a puppy to be born. Collapse Expand CNA Insider contacted Sinogene, Sooam and ViaGen for information on their animal welfare measures and the average number of animals involved in cloning a pet. Sinogene and Sooam did not respond. ViaGen said it is “committed to the health and well-being of each and every dog and cat with whom we work” but did not provide details. A spokesperson said it operates under strict US Department of Agriculture guidelines. “Our team includes leading scientists, and we believe that moving the promising and exciting area of animal genetic research forward will benefit all animals,” the company said. Related:

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  • When was SINOGENE founded?

    SINOGENE was founded in 2012.

  • Where is SINOGENE's headquarters?

    SINOGENE's headquarters is located at Building 310, 311, 312, Building 16, No. 37 Chaoqian Road, Beijing.

  • What is SINOGENE's latest funding round?

    SINOGENE's latest funding round is Series B - III.

  • How much did SINOGENE raise?

    SINOGENE raised a total of $15.63M.

  • Who are the investors of SINOGENE?

    Investors of SINOGENE include Huitianze, Ruijiu Venture Capital, bioVENTURE, Shunxi Fund, Xinuo Hengtong and 6 more.

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