About Sienna Biopharmaceuticals
Sienna Biopharmaceuticals (NASDAQ: SNNA) is a medical dermatology and aesthetics company focused on developing safe and effective targeted therapies to treat inflammatory skin conditions and aesthetic concerns that impact the health and appearance of patients. Through its Topical by Design platform, Sienna is developing its lead assets, SNA-120 (TrkA inhibitor) for pruritus and psoriasis (Phase IIb) and SNA-125 (dual TrkA/JAK3 inhibitor) for atopic dermatitis, psoriasis, and pruritus (proof-of-concept). Through its photoparticle therapy platform, Sienna is developing SNA-001 for the treatment of acne vulgaris (pivotal trials) and for the permanent reduction of unwanted light-pigmented hair (pivotal trials).
Research containing Sienna Biopharmaceuticals
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CB Insights Intelligence Analysts have mentioned Sienna Biopharmaceuticals in 2 CB Insights research briefs, most recently on Aug 29, 2023.
Sienna Biopharmaceuticals Patents
Sienna Biopharmaceuticals has filed 18 patents.
Nanoparticles, Nanomaterials, Nanotechnology, Thermal treatment, Waste treatment technology
Nanoparticles, Nanomaterials, Nanotechnology, Thermal treatment, Waste treatment technology
Latest Sienna Biopharmaceuticals News
Feb 10, 2023
Bill Anderson → You know how we told you last week that we’d keep our eyes peeled for where ex-Roche Pharmaceuticals CEO Bill Anderson turns up next? Well, he gave us an answer in a big way. Anderson will be the CEO at Bayer starting April 1, the German pharma said Wednesday. Unlike Roche, Merck, J&J and the CEO transition that follows, Bayer chose not to go in-house for Werner Baumann’s replacement. Investors have been grumbling about the company’s stock performance, so much so that activist investor Jeff Ubben rallied the troops to find someone outside the company to take control. In the end, the investors won. Shares $BAYRY jumped 6% when news circulated about Anderson’s hiring. Baumann’s retirement after 35 years at Bayer, seven of those as CEO, marks another major change in its leadership. Marianne De Backer, Bayer’s wheeler-dealer who engineered the acquisitions of AskBio and Vividion, will replace George Scangos as CEO of Vir Biotechnology on April 3. Kenji Yasukawa → Astellas will do some shifting of its own, starting at the top with the April 1 departure of Kenji Yasukawa, the president and CEO since 2018. Chief strategy officer Naoki Okamura will take the helm while EVP of corporate strategy Adam Pearson will be elevated to Okamura’s old post. It doesn’t stop there: Chief commercial officer Yukio Matsui will also retire at the same time as Yasukawa, and Claus Zieler — Astellas’ president, established markets commercial — is set to take Matsui’s place. The extensive C-suite shakeup comes as Astellas says a patent cliff and declining revenue is behind it, and the company is ready to go for “aggressive” growth. It also follows the retirement of CMO Bernhardt Zeiher, who spoke with Amber Tong in August 2022 about the gene therapy AT132 for X-linked myotubular myopathy that Astellas picked up from Audentes — and is linked to multiple patient deaths that shook the entire gene therapy landscape. Since Tadaaki Taniguchi succeeded Zeiher on Oct. 1, Astellas scooped up two gene therapy programs from struggling Taysha and saw a clinical hold get lifted for its Pompe disease gene therapy candidate AT845. Scott Myers → Previously known as miRagen, Viridian Therapeutics drew in some serious coin once it trotted out Phase I/II data for its thyroid eye disease drug VRDN-001 in August 2022. But after that $270 million offering, Viridian will have a different conductor leading the way, with Jonathan Violin handing the orchestra to new president and CEO Scott Myers. You may remember Myers from his days as CEO of AMAG Pharmaceuticals, the Makena maker that was sold to Covis Pharma back in 2020. He’s also been chief executive at Rainier Therapeutics and Cascadian Therapeutics. Akin Akinc → Everything’s coming up Alnylam at super-stealthy Feng Zhang upstart Aera Therapeutics, which has tapped Akin Akinc as CEO and John Maraganore as chairman, Business Insider reports . Akinc takes the helm at the gene editing biotech after ending his 19 years at the RNAi titan in September 2022 as head of oncology. Maraganore has populated Peer Review with an endless array of board appointments and advisory roles ever since he stepped down from the top spot at Alnylam. Iya Khalil → A spokesperson for Merck tells Endpoints News that Iya Khalil will join the pharma giant on Feb. 13 as VP and head of data, AI & genome sciences. In a LinkedIn post, Khalil bid farewell to Novartis, where she was global head of the AI innovation laboratory since May 2020. “I want to thank Novartis and all of my colleagues for the unique opportunity to launch the AI lab and NIBR’s commitment to the continued efforts of the AI team under the exceptional leadership of Fiona Marshall,” she wrote. Turnabout is fair play here: Novartis plucked Marshall from Merck to replace Jay Bradner as president of NIBR last fall. Merck has been diving deeper into AI through recent partnerships with Absci, BigHat Biosciences and Saama. Kathy High → STAT writer (and friend of Peer Review) Jason Mast revealed Kathy High’s departure from AAV gene therapy developer AskBio this week. High co-founded Spark Therapeutics and cemented her legacy in the field with her work on the retinal disease drug Luxturna, the first gene therapy to receive FDA approval. Roche ponied up $4.3 billion for Spark, and High then bolted for AskBio in January 2021, becoming the Bayer sub’s president of therapeutics. STAT indicates that High is on sabbatical at Rockefeller University. Dannielle Appelhans → What little remains of Flagship’s Rubius is still scrambling to determine next steps, and while its strategic review rolls on, CEO Dannielle Appelhans’ tenure has been extended from Jan. 31 to “no later than March 3,” an SEC filing states . Meanwhile, it’s Laurence Turka’s turn to leave Rubius after three years as CSO and head of research and translational medicine. Finally, ex-Novartis head of oncology Susanne Schaffert, Francis Cuss and Michael Rosenblatt have all resigned from the board of directors. Behzad Kharabi → TCR biotech T-knife Therapeutics made some noise in 2021 with $110 million in Series B financing and several key hires, including COO Megan Baierlein and CSO Peggy Sotiropoulou. This week T-knife is back with Behzad Kharabi as CMO. Kharabi left J&J for Gilead’s Kite in 2018 and rose to global program clinical lead for Tecartus, the CAR-T therapy that was first approved in the summer of 2020 for relapsed or refractory mantle cell lymphoma. Tecartus then scored another FDA nod a year later for adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia. Nicola Heffron → An SEC filing shows that 2seventy bio COO Nicola Heffron will pack her bags on March 10. No specific reason was given other than the standard line that it wasn’t “due to any disagreement with the Company on any matter.” A Celgene and Shire vet, Heffron jumped over to bluebird bio’s cancer spinout when Nick Leschly split bluebird into the two separate companies in 2021. She started at bluebird in January 2020 as SVP, Europe. Laura Walker → With apologies to Boz Scaggs, the inability of Adagio Therapeutics’ Covid-19 antibody to put up a defense against the Omicron variant signaled a breakdown dead ahead for the Tillman Gerngross biotech. Gerngross gave up his spot as CEO, the company rebranded as Invivyd, layoffs ensued , and multiple execs walked out the door. The latest is CSO Laura Walker, who co-founded Adagio and has also worked at Adimab (another Gerngross joint). Interim head of discovery and preclinical Lukas Dillinger will handle CSO duties until Invivyd finds her replacement. Anders Ullman → Only a year into his tenure as head of R&D and medical affairs and CMO at Sobi, Anders Ullman has decided to retire on April 1. Tony Hoos, who will take over for the 67-year-old Ullman, has led the global rare disease business unit at GSK and is the former head of medical in Europe for Amgen. Additionally, Hoos spent a year as medical chief of Flagship’s Valo Health. Ullman was a board member at Sobi before he replaced Ravi Rao, the current CMO with Oxford Biomedica and Sitryx. Laetitia Rouxel → On April 1, Laetitia Rouxel will become the CFO of German-based Evotec, which boasts a slew of discovery partnerships from a who’s who in the pharma world — Eli Lilly, Boehringer Ingelheim, Novo Nordisk and Bristol Myers Squibb among them. An 11-year Pfizer vet, Rouxel has been divisional finance chief for beauty and fragrance company Coty and global CFO of Dutch plastic pipe provider Wavin. Enno Spillner, Evotec’s CFO since 2016, is leaving at the end of next month when his contract runs out. Tracey Sacco → Scholar Rock’s first-year CEO and ex-Acceleron R&D chief Jay Backstrom has lined up a familiar face to take on the role of chief commercial officer. Tracey Sacco joined Acceleron in 2012 as senior director, corporate development and would later work on the product launch of the Bristol Myers-partnered drug Reblozyl. She was SVP, global strategic marketing when Merck bought the biotech for $11.5 billion in the fall of 2021. Scholar Rock hasn’t evaded the onslaught of layoffs in the industry, trimming 25% of its staff in May 2022. Gopi Shankar → Friedreich’s ataxia specialist Larimar Therapeutics has appointed Gopi Shankar as chief development officer. Shankar just had a 12-year run at J&J and had been Janssen’s VP and global head, biologics development sciences since 2018. Larimar waited out a clinical hold for its Friedreich’s ataxia candidate CTI-1601 that lasted more than a year until it was lifted in September 2022 . However, a partial hold on the drug is still in place. → Another hire has bubbled up at T cell engager biotech Lava Therapeutics, with Charles Morris taking the CMO reins from Benjamin Winograd. Morris recently held the same title at Celyad Oncology, a biotech hanging on by its fingernails after cutting the cord on development of its allogeneic BCMA CAR-T, CYAD-211. He also spent two years as medical chief of Radius Health, the now-private company acquired by Gurnet Point Capital and Jim Momtazee’s Patient Square Capital last summer. Toshiya Nishi → Jeremy Levin’s Ovid is bringing in a new duo with the hiring of Manoj Malhotra as CMO and Toshiya Nishi as epilepsy research head. Malhotra, who’s known Levin for some time, joins the team from Eisai’s neurology business group and has prior stints at Mallinckrodt, Novartis and Takeda under his belt. Meanwhile, Nishi comes to the company from Takeda, where he co-invented soticlestat. In his new role, Nishi will be focused on preclinical development, specifically KCC2. John Kauh → Going after STAT3 with its lead asset TTI-101, Houston’s Tvardi Therapeutics has recruited John Kauh as CMO. As VP of clinical development at Hutchmed, Kauh worked on surufatinib, a drug that got dinged with a CRL last year as part of the FDA’s broader clampdown on China-only trial data. Tvardi, co-founded by the University of Texas MD Anderson Cancer Center’s Ron DePinho, last raised cash in June 2021 with a $74 million Series B . Roger Sidhu → New York cancer biotech Treadwell Therapeutics has welcomed Roger Sidhu as CMO. Sidhu previously showed up in Peer Review when he left Roivant in September 2021 to become medical chief at Brooklyn ImmunoTherapeutics, now named Eterna Therapeutics. Sidhu was VP of clinical development at Kite before landing the CMO and head of R&D posts at Roivant in 2020. → David Gaiero has been promoted to CFO of Cyteir Therapeutics, which laid off 70% of its staff last month and is down to 15 employees who will redouble the Lexington, MA biotech’s efforts in ovarian cancer with a combo therapy of CYT-0851 and capecitabine. Gaiero was named VP of finance at Cyteir in December 2020 after three years as VP, corporate controller and interim CFO at Wave Life Sciences. Robert McRae → Back in September, Palisade Bio downsized its team of 13 by 20% to keep pushing forward with development of its lead candidate. Now, the Carlsbad, CA-based company is promoting Robert McRae to the position of COO. McRae has been with the company since December 2021, having joined as SVP, operations and strategic development. Prior to Palisade, McRae was with Viracta Therapeutics as VP, operations & strategic alliances. In addition to McRae’s promotion, interim CEO JD Finley is grabbing a seat on the company’s board of directors. JP Gabriel → JP Gabriel has been named chief technical operations officer at RNAi player Silence Therapeutics after the retirement of SVP, technical operations and Ferring vet Jørgen Wittendorff. Gabriel has held positions in manufacturing and quality at Roche/Genentech, Ultragenyx and most recently, Ocugen, where he was SVP, technical operations. Almost a year ago, Craig Tooman succeeded Mark Rothera as Silence’s CEO in a shakeup that involved the promotion of Rhonda Hellums to Tooman’s old CFO job. Rothera now runs the show at Viracta Therapeutics. → Shanghai MicuRx Pharmaceutical has pulled in Regis Vilchez as CMO of its American subsidiary, MicuRx Pharmaceuticals. Vilchez is bringing with him experience from his time spent at Boehringer Ingelheim, Merck, Roche, Abbott/AbbVie and Mallinckrodt. During his career, Vilchez has contributed to the global development of a number of therapies, including Victrelis, Ocaliva and StrataGraft. Didier Vingadassalom → Didier Vingadassalom gets his own cadenza in this portion of Peer Review as senior director, business development at Concerto Biosciences. Vingadassalom is a Sanofi alum who comes from SQZ Biotechnologies, where he was senior director, business development and head of alliance management. Co-founded by CEO Cheri Ackerman and CSO Jared Kehe — both trained pianists — microbe-focused Concerto hit the stage three months ago with $23 million in Series A funding . → Blue Water Vaccines, which back in August ditched SPAC merger plans , has reeled in Frank Jaeger as SVP of marketing and business development. Jaeger hails from Clarus Therapeutics, where he was SVP and CCO. Before that, Jaeger was with the team at AbbVie, helping launch AndroGel from its men’s health business unit. Biren Amin → Biren Amin has joined the board of directors at ImmPACT Bio, a CAR-T outfit chaired by ex-Gossamer Bio CEO Sheila Gujrathi. Since leaving Jefferies in 2021, Amin has been finance chief at Immuneering and now tackles the roles of CFO and chief strategy officer for Pyramid Biosciences. → Ex-Blueprint Medicines chief Jeff Albers has been named chairman of the board at MOMA Therapeutics, a Third Rock biotech that raised $150 million in a Series B round last May. Albers, who’s still chairman at Blueprint, started a gig at Atlas Venture last month as a venture partner. Barbara Duncan → In its first Peer Review appearance since buying Antares Pharma for just shy of $1 billion last April, Halozyme has elected Barbara Duncan to the board of directors. Duncan was CFO of Intercept from 2009-16 and chairs the board at Fusion Pharmaceuticals. → Touting a Phase II win with the ex-Amgen drug obicetrapib last month, NewAmsterdam Pharma has elected John Smither to the board of directors. Smither is an Amgen vet whose past CFO appointments include Sienna Biopharmaceuticals (two separate stints), Kite (interim) and Arcutis. Marcella Ruddy → Sam Truex’s Upstream Bio flowed onto our radar with a $200 million debut last June, and this week the inflammatory disease biotech has reserved space for Tectonic Therapeutic CMO Marcella Ruddy on the board of directors. To conclude her five years at Regeneron, Ruddy was VP, clinical development for inflammation and immunology from 2018-21. → Waypoint Holdings chairman and CEO Thomas Dietz is headed to the board of directors at RNA player Nutcracker Therapeutics. Dietz, the chairman of Eiger BioPharmaceuticals, owns board seats at Paratek Pharmaceuticals and Leap Therapeutics. Lin Guey → Carisma Therapeutics, the company that took the spotlight with its CAR-M therapy , is bringing in some firepower from one of its allies to its team. Moderna’s Lin Guey, who oversees the partnership between the two companies, will be joining Carisma’s scientific advisory board. During her career, Guey has worked at Tessera, Xilio, Shire and Pfizer. → Repligen has named ex-Millipore CEO Martin Madaus to its board of directors. Madaus is a senior operating executive at The Carlyle Group and the former North America president and CEO of Roche Diagnostics. → The chief marketing officer of Evolus, Crystal Muilenburg, is hopping onto the board of directors at Elevai Labs. While at Evolus, Muilenburg has helped lead the re-launch of Jeuveau. Prior to Evolus, Muilenburg was with Sienna Biopharmaceuticals and had a decade-long stint at Allergan. → Acticor Biotech, which recently revised its pipeline to postpone a Phase II study, has pulled out a seat on its board of directors for Patricia Zilliox — who will be replacing Corinne Le Goff. Zilliox serves as president and CEO of Eyevensys and has held roles at Alcon Laboratories and the Clinical Research Institute. → Boston-based Anodyne Nanotech, dealing with microneedle tech, has brought on Jeff Mihm to its board of directors. Mihm formerly served as CEO of Noven Pharmaceuticals. AUTHORS Beth Snyder Bulik Senior Editor Menopause is about to have a big moment — at the Super Bowl. Astellas is taking its hot flashes and night sweats awareness campaign to Sunday’s broadcast. The 30-second Astellas commercial running during the game centers on the technical term, vasomotor symptoms or VMS, for those common menopause signals. In the ad, actress Carmella Riley is a reporter on the street stopping women to ask them “one burning question,” which is: “What is VMS?” Keep reading Endpoints with a free subscription Unlock this story instantly and join 159,200+ biopharma pros reading Endpoints daily — and it's free. SIGN UP Remember how good 2020 was for biotech venture numbers? Now hold that thought. Diving into the numbers for life science venture investors last year, DealForma’s Chris Dokomajilar tracked a dramatic downturn in 2022, setting the stage for a new normal that puts healthcare back at levels registered in 2019 and 2020. But biopharma was singled out for some rough handling once you break them out of the pack. In his annual look at the top 100 investors in biotech, Dokomajilar found that close to $20 billion of the $51 billion in life sciences investments tracked last year were directed at platforms and therapeutics. Premium subscription required Jared Whitlock Features Editor Don Kyle spent more than 20 years working for Purdue Pharma, right through the US opioid epidemic that led to the company’s rise and eventual infamy. But contrary to Purdue’s focus on OxyContin, Kyle was researching non-opioid painkillers — that is, until the company shelved his research. As the company’s legal troubles mounted, Kyle found an unlikely way to reboot the project. In 2019, he took his work to an Oklahoma State University center that’s slated to receive more than two-thirds of the state’s $272 million settlement with Purdue over claims that the drugmaker’s behavior ignited the epidemic of opioid use and abuse. Premium subscription required Beth Snyder Bulik Senior Editor Crooked vegetables served as effective props in Endo Pharmaceuticals’ first awareness campaign for Peyronie’s disease and unnatural penile curvature, but now it’s taking a different tack. Its new “Man With a Plan” awareness campaign debuted this week and shows men searching the internet for answers. Men in darkened rooms, faces illuminated by a computer or phone screen, type into search boxes with queries such as: “What causes a curve down there?” and “Will it get worse?” The TV ad is running along with digital, social media, print and in-office promotions in the newly launched “Plan” campaign. Keep reading Endpoints with a free subscription Unlock this story instantly and join 159,200+ biopharma pros reading Endpoints daily — and it's free. SIGN UP LOG IN
Sienna Biopharmaceuticals Frequently Asked Questions (FAQ)
Where is Sienna Biopharmaceuticals's headquarters?
Sienna Biopharmaceuticals's headquarters is located at 30699 Russell Ranch Road, Westlake Village.
What is Sienna Biopharmaceuticals's latest funding round?
Sienna Biopharmaceuticals's latest funding round is Dead.
How much did Sienna Biopharmaceuticals raise?
Sienna Biopharmaceuticals raised a total of $86M.
Who are the investors of Sienna Biopharmaceuticals?
Investors of Sienna Biopharmaceuticals include ARCH Venture Partners, Altitude Life Science Ventures, PFM Health Sciences, VenVest Capital, Clough Global and 7 more.