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ribontx.com

Founded Year

2015

Stage

Series C | Alive

Total Raised

$163.5M

Last Raised

$65M | 1 yr ago

About Ribon Therapeutics

Ribon Therapeutics specializes in the development and discovery of monoPARP (mono ADP-ribose polymerase) inhibitors to block cancer cells' fundamental ability to survive under stress.

Ribon Therapeutics Headquarter Location

35 Cambridgepark Drive

Cambridge, Massachusetts, 02140,

United States

617-914-8700

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Expert Collections containing Ribon Therapeutics

Expert Collections are analyst-curated lists that highlight the companies you need to know in the most important technology spaces.

Ribon Therapeutics is included in 2 Expert Collections, including Cancer.

C

Cancer

4,784 items

Pharmaceutical and biotechnology companies with cancer therapy drug candidates.

B

Biopharma Tech

838 items

Ribon Therapeutics Patents

Ribon Therapeutics has filed 6 patents.

The 3 most popular patent topics include:

  • Transcription factors
  • Proteins
  • Clusters of differentiation
patents chart

Application Date

Grant Date

Title

Related Topics

Status

4/29/2019

4/5/2022

Molecular biology, Microscopy, Transcription factors, Fluorescence, Biotechnology

Grant

Application Date

4/29/2019

Grant Date

4/5/2022

Title

Related Topics

Molecular biology, Microscopy, Transcription factors, Fluorescence, Biotechnology

Status

Grant

Latest Ribon Therapeutics News

Every-other-week dose of dupilumab safe, effective over long term

May 12, 2022

Beck LA, et al. 2022;doi:10.1007/s40257-022-00685-0. Disclosures: Beck reports being an investigator and/or consultant for AbbVie, Allakos, Arena Pharmaceuticals, AstraZeneca, Benevolent AI, DermTech, Galderma, Incyte, Janssen, Kiniksa Pharmaceuticals, LEO Pharma, Lilly, Novartis, Numab Therapeutics, Pfizer, Principia Biopharma, RAPT Therapeutics, Regeneron Pharmaceuticals, Ribon Therapeutics, Sanofi, Sanofi-Aventis, Stealth BioTherapeutics and Union Therapeutics; and owning stock in 3M, Gilead, Medtronic and Moderna. Please see the study for all other authors’ relevant financial disclosures. ADD TOPIC TO EMAIL ALERTS Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . Subscribe ADDED TO EMAIL ALERTS Back to Healio We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com . Back to Healio A dosing change from once a week to every other week did not diminish the long-term efficacy or safety of dupilumab in certain patients with atopic dermatitis, according to analysis findings. “Moderate to severe atopic dermatitis (AD) often requires long-term management with systemic therapies,” Lisa A. Beck, MD, of the department of dermatology at the University of Rochester Medical Center in Rochester, New York, and colleagues wrote. The interim analysis evaluated the findings of an open-label extension study investigating the safety and efficacy of a change in dosing schedule of dupilumab (Dupixent, Sanofi Genzyme/Regeneron) in this patient population. Participants transitioned from weekly dupilumab 300 mg to a dose every other week. The analysis included 2,677 enrolled and treated patients. Beck and colleagues reported that 352 of those patients completed efficacy assessments through week 204, while 202 completed follow-up safety assessments through week 244. Patients complied with treatment at a rate of 98.1%, according to self-reported data. There were no changes in the safety profile of dupilumab as compared with previous trials. Nasopharyngitis, AD, upper respiratory tract infections, oral herpes, conjunctivitis, injection-site reactions and headaches each occurred in 5% or fewer patients. Efficacy results from week 204 showed that mean EASI scores were 2.46 (standard deviation [SD], ± 3.98), which the researchers noted was a 91.07% change from parent study baseline. Pruritis Numerical Rating Scale scores were 2.1 (SD, ± 1.83), which represented a mean percent change from the parent study baseline of 68.74%. Among 226 patients who transitioned from once-weekly to every-other-week dosing, efficacy of dupilumab was maintained. The open-label nature of the study, along with the lack of a control arm, may limit the applicability of these findings. In addition, a smaller subset of patients received the approved every-other-week dose. “These results support dupilumab as continuous long-term treatment for adults with moderate to severe AD,” the researchers concluded. Read more about

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  • When was Ribon Therapeutics founded?

    Ribon Therapeutics was founded in 2015.

  • Where is Ribon Therapeutics's headquarters?

    Ribon Therapeutics's headquarters is located at 35 Cambridgepark Drive, Cambridge.

  • What is Ribon Therapeutics's latest funding round?

    Ribon Therapeutics's latest funding round is Series C.

  • How much did Ribon Therapeutics raise?

    Ribon Therapeutics raised a total of $163.5M.

  • Who are the investors of Ribon Therapeutics?

    Investors of Ribon Therapeutics include U.S. Venture Partners, Deerfield Management, The Column Group, Osage University Partners, Euclidean Capital and 13 more.

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