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oncoresponseinc.com

Founded Year

2015

Stage

Line of Credit | Alive

Total Raised

$153.1M

Last Raised

$50M | 7 mos ago

About OncoResponse

OncoResponse mines the human adaptive immune system to discover therapeutic antibodies against immuno-oncology targets. By identifying candidates from the immune systems of patients who have responded exceptionally well to cancer immunotherapies, OncoResponse has the potential to increase the success rate of these therapies across multiple cancer types.

OncoResponse Headquarters Location

1124 Columbia St Suite 300

Seattle, Washington, 98104,

United States

206-805-1600

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Expert Collections containing OncoResponse

Expert Collections are analyst-curated lists that highlight the companies you need to know in the most important technology spaces.

OncoResponse is included in 3 Expert Collections, including Cancer.

C

Cancer

4,784 items

Pharmaceutical and biotechnology companies with cancer therapy drug candidates.

R

Regenerative Medicine

1,818 items

Regenerative medicine refers to the process of activating, replacing, engineering or regenerating human genetic material, cells, tissues or organs to restore normal function. It also includes bioengineered tissues used for in vitro testing (e.g. organ-on-a-chip, organoids).

B

Biopharma Tech

15,535 items

Companies involved in the research, development, and commercialization of chemically- or biologically-derived therapeutic & theranostic drugs. Excludes vitamins/supplements, CROs/clinical trial services.

OncoResponse Patents

OncoResponse has filed 3 patents.

The 3 most popular patent topics include:

  • Clusters of differentiation
  • Experimental cancer drugs
  • Immune system
patents chart

Application Date

Grant Date

Title

Related Topics

Status

7/22/2020

6/15/2021

Monoclonal antibodies, Immune system, Clusters of differentiation, Immunology, Experimental cancer drugs

Grant

Application Date

7/22/2020

Grant Date

6/15/2021

Title

Related Topics

Monoclonal antibodies, Immune system, Clusters of differentiation, Immunology, Experimental cancer drugs

Status

Grant

Latest OncoResponse News

08:00 EDT OncoResponse Announces Clinical Supply Agreement with Regeneron to Evaluate OR2805 in Combination with Libtayo® (cemi...

Sep 7, 2022

News provided by Share this article Share this article SEATTLE, Sept. 7, 2022 /PRNewswire/ -- OncoResponse, a clinical-stage biotech company advancing immunotherapies derived from the immune systems of elite cancer responders, today announced a clinical supply agreement with Regeneron for PD-1 inhibitor Libtayo® (cemiplimab). The supply agreement will support the evaluation of Libtayo in combination with OR2805, a fully human monoclonal antibody identified from an elite cancer responder using OncoResponse's proprietary B-cell discovery platform. "We believe the ability of OR2805 to potently activate myeloid cells within the tumor microenvironment will not only provide benefit as a monotherapy, but also improve responses to currently available checkpoint inhibitor immunotherapies such as Libtayo," said Bob Lechleider, MD, Chief Medical Officer of OncoResponse. "We look forward to evaluating the combination of OR2805 with Libtayo, which has demonstrated efficacy in pivotal trials, serving as the basis for FDA approval in three types of advanced cancers. We believe that this combination treatment approach has the potential to improve the outcomes of patients with cancer." OR2805 is being evaluated in an ongoing Phase 1 study examining safety, pharmacokinetics and preliminary anti-cancer activity in patients with advanced solid tumors alone and in combination with anti-PD-1 therapy. The trial includes a dose escalation phase, followed by several expansion cohorts. The role of potential biomarkers will be evaluated throughout the study, and more intensively in a separate biology cohort. ClinicalTrials.gov  identifier: NCT05094804 About OR2805 OR2805 is a fully human antibody discovered using B cells derived from an elite responder to checkpoint inhibitor (CPI) therapy. This antibody binds to CD163 which is highly expressed on tumor associated macrophages (TAMs) that create an immunosuppressive tumor microenvironment and inhibit anti-tumor T-cell responses. High frequency of CD163-expressing TAMs generally predicts an unfavorable prognosis in solid tumors. OR2805 is designed to improve anti-tumor T-cell responses, by reversing the immunosuppression of TAMs, as a therapeutic strategy for monotherapy and in combination with CPI. About OncoResponse OncoResponse is a clinical-stage, immuno-oncology biotech company developing cancer immunotherapies using clues from the immune systems of elite cancer responders. In a broad strategic alliance with MD Anderson Cancer Center, OncoResponse deploys a proprietary B-cell discovery platform to identify and develop novel therapeutics targeting the tumor microenvironment. The company's lead candidate, OR2805, has entered clinical studies. OR2805 is a fully human antibody discovered using B cells derived from an elite responder to checkpoint inhibitor (CPI) therapy. Additional pipeline candidates that modulate suppressive macrophage activity are under development. OncoResponse is a privately held company backed by investment from MD Anderson Cancer Center, Rivervest Venture Partners, Qatar Investment Authority, Redmile Group, Magnetar Group, Yonjin Venture, InterVest, Bering Capital, ARCH Venture Partners, Helsinn Investment Fund, Canaan Partners, GreatPoint Ventures, Takeda Ventures, Buchang Pharma, Alexandria Real Estate Equities and William Marsh Rice University. For more information please visit  www.oncoresponse.com and follow us on LinkedIn and Twitter . Media Contact:

OncoResponse Web Traffic

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  • When was OncoResponse founded?

    OncoResponse was founded in 2015.

  • Where is OncoResponse's headquarters?

    OncoResponse's headquarters is located at 1124 Columbia St, Seattle.

  • What is OncoResponse's latest funding round?

    OncoResponse's latest funding round is Line of Credit.

  • How much did OncoResponse raise?

    OncoResponse raised a total of $153.1M.

  • Who are the investors of OncoResponse?

    Investors of OncoResponse include Oxford Finance, 3B Future Health Fund, ARCH Venture Partners, Canaan Partners, Redmile Group and 14 more.

  • Who are OncoResponse's competitors?

    Competitors of OncoResponse include Epsilogen, Immune-Onc Therapeutics, Fortis Therapeutics, Pionyr Immunotherapeutics, Neon Therapeutics and 9 more.

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