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NanoCor Therapeutics

nanocorthx.com

Founded Year

2005

Stage

Unattributed - II | Alive

Total Raised

$6.25M

Last Raised

$2.5M | 13 yrs ago

About NanoCor Therapeutics

NanoCor Therapeutics is a biotechnology company founded to create a viable intracellular genetic protein therapy for the treatment of Chronic Heart Failure (CHF)

Headquarters Location

870 Martin Luther King Junior Boulevard

Chapel Hill, North Carolina, 27514,

United States

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Expert Collections containing NanoCor Therapeutics

Expert Collections are analyst-curated lists that highlight the companies you need to know in the most important technology spaces.

NanoCor Therapeutics is included in 1 Expert Collection, including Biopharma Tech.

B

Biopharma Tech

5,241 items

Companies involved in the research, development, and commercialization of chemically- or biologically-derived therapeutic & theranostic drugs. Excludes vitamins/supplements, CROs/clinical trial services.

NanoCor Therapeutics Patents

NanoCor Therapeutics has filed 1 patent.

patents chart

Application Date

Grant Date

Title

Related Topics

Status

12/23/2008

3/26/2013

RNA interference, RNA, MicroRNA, Gene expression, Molecular biology

Grant

Application Date

12/23/2008

Grant Date

3/26/2013

Title

Related Topics

RNA interference, RNA, MicroRNA, Gene expression, Molecular biology

Status

Grant

Latest NanoCor Therapeutics News

AskBio initiates Phase I trial of gene therapy for heart failure

Feb 5, 2020

Share 7 mins ago Asklepios BioPharmaceutical (AskBio) and its subsidiary NanoCor Therapeutics have dosed the first patient in a Phase I clinical trial of gene therapy candidate NAN-101 to treat congestive heart failure. Congestive heart failure is characterised by the inability of the heart to supply the necessary blood and oxygen to the body. The condition lacks cure, while drugs and surgical therapy are intended to alleviate symptoms and slow damage. NAN-101 is an adeno-associated virus (AAV) gene therapy designed to stimulate protein phosphatase inhibitor 1 (I-1c) to block the action of protein phosphatase 1 (PP1), which is linked to heart failure. The medication is directly given to the heart via an intracoronary infusion. The NAN-CS101 open-label, dose-escalation, multi-centre trial will evaluate three doses of the gene therapy in approximately 12 patients with NYHA Class III heart failure. The primary objective of the study is safety, along with the effect of NAN-101 on patient health, which is tracked as changes in exercise capacity, heart function, and quality of life. AskBio chief scientific officer and co-founder Jude Samulski said: “Dosing the first patient using gene therapy to target I-1c to improve heart function is a tremendous milestone not only for the AskBio and NanoCor teams but, more importantly, for patients whose quality of life is negatively affected by CHF. “We initially developed this gene therapy as treatment for late-stage Duchenne muscular dystrophy patients who typically die from cardiomyopathy. Following preclinical studies, we observed that heart function improved, which led us to investigate treatment for all types of heart failure.” The Phase I trial is expected to be completed in July next year. What you should read next

NanoCor Therapeutics Frequently Asked Questions (FAQ)

  • When was NanoCor Therapeutics founded?

    NanoCor Therapeutics was founded in 2005.

  • Where is NanoCor Therapeutics's headquarters?

    NanoCor Therapeutics's headquarters is located at 870 Martin Luther King Junior Boulevard, Chapel Hill.

  • What is NanoCor Therapeutics's latest funding round?

    NanoCor Therapeutics's latest funding round is Unattributed - II.

  • How much did NanoCor Therapeutics raise?

    NanoCor Therapeutics raised a total of $6.25M.

  • Who are the investors of NanoCor Therapeutics?

    Investors of NanoCor Therapeutics include Medtronic.

  • Who are NanoCor Therapeutics's competitors?

    Competitors of NanoCor Therapeutics include Bloomage BioTech, Zymeworks, Dendreon, Cebix, Tau Therapeutics and 10 more.

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