Search company, investor...
Michigan State University company logo

Michigan State University

msu.edu

Founded Year

1855

Stage

Grant - III | Alive

Total Raised

$4.27M

Last Raised

$300K | 4 yrs ago

About Michigan State University

Michigan State University is an educational institution operating in the higher education sector. The university offers a wide range of academic programs, including undergraduate and graduate degrees, in various fields of study. It primarily serves students seeking higher education. It was founded in 1855 and is based in East Lansing, Michigan.

Headquarters Location

426 Auditorium Road

East Lansing, Michigan, 48824,

United States

+1 517 355 1855

Loading...

Loading...

Michigan State University Patents

Michigan State University has filed 2 patents.

The 3 most popular patent topics include:

  • acetic acids
  • analog circuits
  • capacitors
patents chart

Application Date

Grant Date

Title

Related Topics

Status

3/23/2021

1/31/2023

Radio-frequency identification, Ubiquitous computing, Capacitors, Electric power conversion, Analog circuits

Grant

Application Date

3/23/2021

Grant Date

1/31/2023

Title

Related Topics

Radio-frequency identification, Ubiquitous computing, Capacitors, Electric power conversion, Analog circuits

Status

Grant

Latest Michigan State University News

Scientists Uncover Key to Tastier and Healthier Potato Chips

Feb 22, 2024

By Michigan State University February 21, 2024 Scientists have discovered a mechanism to prevent darkening and health risks in cold-stored potatoes, a breakthrough promising healthier, tastier snacks and addressing a billion-dollar market’s challenges. Their work, revealing a gene responsible for cold-induced sweetening (CIS), could lead to new potato varieties that avoid acrylamide formation, benefiting the snack food industry and potentially reducing food waste and costs. Researchers at Michigan State University have discovered a method to decrease the levels of a carcinogen generated during the frying of tubers that have been stored in cold conditions. In a breakthrough for the snack food industry, a team of scientists led by Michigan State University professors Jiming Jiang and David Douches has discovered a key mechanism behind the darkening and potential health concerns associated with cold-stored potatoes. Their findings, published in the journal The Plant Cell, hold promise for the development of potato varieties that could be stored under cold temperatures and lead to healthier and tastier chips and fries. These snacks have a market worth billions of dollars in the U.S. In Michigan — the nation’s leading producer of potatoes for chips — the potato industry is valued at $240 million annually. Michigan State University researchers David Douches (left) and Jiming Jiang (right) work with potato plants in Michigan State University’s Agronomy Farm Greenhouse. Credit: Paul Henderson/MSU But farmers can’t grow the crops year-round and snack makers need a constant supply of fresh spuds to meet their demands. Preserving potatoes in cold storage ensures chip and fry producers have what they need, but the low temperatures also trigger a process called cold-induced sweetening, or CIS, which converts starches to sugars. Processing tubers loaded with sugars results in darkened fries and chips. It also generates acrylamide, a carcinogenic compound formed during high-temperature processing, which has been linked to health concerns including an increased cancer risk. Although there are techniques to reduce sugars in cold-stored tubers, these add cost and can affect the flavor of the final product. So Jiang and his colleagues have focused on the root of the problem to work toward potatoes that aren’t affected by CIS, to begin with. “We’ve identified the specific gene responsible for CIS and, more importantly, we’ve uncovered the regulatory element that switches it on under cold temperatures,” explained Jiang, an MSU Research Foundation Professor in the departments of Plant Biology and Horticulture. “By studying how this gene turns on and off, we open up the possibility of developing potatoes that are naturally resistant to CIS and, therefore, will not produce toxic compounds.” By switching off the potato vacuolar invertase gene, or VInv, Michigan State University researchers have shown that frying potatoes stored at cold temperatures can result in a healthier and more appealing chip. Credit: Adapted from Bhaskar, P.B., et al. Plant Physiology, 2010, 154 (2), 939–948, https://doi.org/10.1104/pp.110.162545 From lab, to greenhouse, to chip bag Jiang, a potato researcher for over 20 years, has dedicated his career to solving this puzzle. To overcome one of the most pressing issues in the potato industry, Jiang started his work to minimize acrylamide in potato chips and fries at the University of Wisconsin-Madison. There, Jiang and his team published a paper in 2010 identifying a key gene responsible for potato CIS. Moving to MSU in 2017, Jiang and his team have worked to pinpoint which elements of that gene could be modified to stop the process of cold-induced sweetening. Jiang’s research team, which includes collaborators across MSU’s campus as well as at other research universities, used a combination of gene expression analysis, protein identification, and enhancer mapping to pinpoint the regulatory element controlling the CIS gene. “MSU’s collaborative research environment and facilities, including the world-class potato breeding program led by Dave Douches, were instrumental for this research,” Jiang said. “Our next steps involve using this knowledge to create CIS-resistant potato lines through gene editing or other breeding techniques in Dr. Douches’ greenhouses.” Researchers are growing healthier, more snackable potatoes in Michigan State University’s Agronomy Farm Greenhouse. Credit: Paul Henderson/MSU The lead of the MSU Potato Breeding and Genetics Program, Douches put into practice a technique Jiang developed to stop CIS through gene editing. “All our facilities are on campus so the research work can be done efficiently,” Douches said. “With our collaboration, we were able to produce a finding that paves the way for targeted genetic modification approaches to create cold-resistant potato varieties.” The potential benefits of this research extend beyond improved snack food quality. Reducing acrylamide formation in potatoes could have implications for other processed starchy foods. Additionally, cold-resistant potatoes could offer greater flexibility in storage and transportation, potentially reducing food waste and costs. Jiang believes the new CIS-resistant potatoes could be commercially available in the near future. “This discovery represents a significant advancement in our understanding of potato development and its implications for food quality and health,” Jiang said. “It has the potential to affect every single bag of potato chips around the world.” Reference: “Molecular dissection of an intronic enhancer governing cold-induced expression of the vacuolar invertase gene in potato” by Xiaobiao Zhu, Airu Chen, Nathaniel M Butler, Zixian Zeng, Haoyang Xin, Lixia Wang, Zhaoyan Lv, Dani Eshel, David S Douches and Jiming Jiang, 20 February 2024, The Plant Cell.

Michigan State University Frequently Asked Questions (FAQ)

  • When was Michigan State University founded?

    Michigan State University was founded in 1855.

  • Where is Michigan State University's headquarters?

    Michigan State University's headquarters is located at 426 Auditorium Road, East Lansing.

  • What is Michigan State University's latest funding round?

    Michigan State University's latest funding round is Grant - III.

  • How much did Michigan State University raise?

    Michigan State University raised a total of $4.27M.

  • Who are the investors of Michigan State University?

    Investors of Michigan State University include U.S. Economic Development Administration and The Andrew W. Mellon Foundation.

Loading...

Loading...

CBI websites generally use certain cookies to enable better interactions with our sites and services. Use of these cookies, which may be stored on your device, permits us to improve and customize your experience. You can read more about your cookie choices at our privacy policy here. By continuing to use this site you are consenting to these choices.