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medalliance.com

Stage

Private Equity | Alive

Total Raised

$30M

About MedAlliance

MedAlliance is a privately-owned medical technology company that focuses on developing medical products for the treatment of coronary and peripheral artery disease. The company's DCB technology is a next-generation approach for patients with peripheral artery disease (PAD), coronary artery disease (CAD), and arteriovenous fistulas (AVF). With unique micro-reservoirs, the technology efficiently delivers sirolimus to the target lesion, where it provides controlled and sustained release. MedAlliance's technology will further enable surgeons' desire to move away from metal scaffolds and durable polymers that remain within the patient in PAD by providing a safer and more effective alternative to paclitaxel-coated balloons.

MedAlliance Headquarters Location

Rue de Rive 5

Nyon, 1260,

Switzerland

+ 41 22 363 78 90

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Research containing MedAlliance

Get data-driven expert analysis from the CB Insights Intelligence Unit.

CB Insights Intelligence Analysts have mentioned MedAlliance in 1 CB Insights research brief, most recently on Mar 26, 2020.

Expert Collections containing MedAlliance

Expert Collections are analyst-curated lists that highlight the companies you need to know in the most important technology spaces.

MedAlliance is included in 3 Expert Collections, including Medical Devices.

M

Medical Devices

8,687 items

Companies developing medical devices (per the IMDRF's definition of "medical device"). Includes software, lab-developed tests (LDTs), and combination products. *Columns updated as regularly as possible.

R

Regenerative Medicine

1,818 items

Regenerative medicine refers to the process of activating, replacing, engineering or regenerating human genetic material, cells, tissues or organs to restore normal function. It also includes bioengineered tissues used for in vitro testing (e.g. organ-on-a-chip, organoids).

H

Health IT

7,901 items

Latest MedAlliance News

First patient enrolled in Erectile Dysfunction prospective randomized study with SELUTION SLR

Sep 11, 2022

PRNewsWire India GENEVA, Switzerland, Sept. 10, 2022 /PRNewswire/ -- An 82-year-old Taiwanese man has become the first patient to be enrolled in the initial Erectile Dysfunction (ED) randomized clinical trial (RCT) involving SELUTION SLR™, MedAlliance's novel sirolimus-eluting balloon. The PERFECT-SELUTION FIM (PElvic Revascularization For EreCTile dysfuction-SELUTION First-In-Man) study involves a total of 54 patients suffering from distal internal pudendal-penile artery stenotic disease and ED. They are being randomized to treatment with either SELUTION SLR or plain old balloon angioplasty (POBA), then followed-up for a period of 12 weeks. The primary efficacy endpoint of the study is angiographic binary restenosis (>50% lumen diameter stenosis) defined by computer tomography (CT) and the primary safety endpoint is the rate of major adverse events. "We are excited to begin this study on such a long-suffering patient population. We hope that this study will give these patients a better chance of a normal life, and look forward to the results," said Tzung-Dau Wang, Professor of Medicine and Director of Cardiac Cath Lab, National Taiwan University Hospital, who has performed pudendal and penile artery angioplasty with conventional devices ( POBA and/or stents) on more than 500 patients with arteriogenic erectile dysfunction and acknowledged that restenosis occurred in more than 30% of treated patients. "We do need a state-of-the-art technology to break this barrier. We are pleased to initiate this study: the first patient has responded well to this therapy. ""We have been very pleased with the clinical results of this technology in many applications: in-stent restenosis, coronary de novo, both below and above the knee, AV fistula and now erectile dysfunction. This combination drug-device technology seems to be very versatile, and we look forward to the results from this physician-initiated study, as this is clearly an unmet need touching the lives of hundreds of millions people," added Jeffrey B. Jump, Chairman and CEO of MedAlliance.This study follows a successful feasibility study conducted in Europe in August 2021, involving ten patients with ED.It is estimated that over 300 million men worldwide were affected by ED in 2020, a figure projected to increase to 322 million by 2025. Nearly 30% of these were aged between 40 and 70. The most common cause of ED is vascular disease. 70% of physical-related causes of ED are due to reduced blood circulation to the penis. PDE5 inhibitors (e.g. Viagra, Cialis) are the most commonly used form of drug treatment for ED, but up to 50% of those patients treated, experience a suboptimal response. A potential alternative therapy for these patients is to treat the pudendal and/or penile arteries via the percutaneous approach, using a coronary metallic stent or a balloon. Atherosclerotic occlusive disease of the ilio-pudendal-penile arteries resulting in arterial insufficiency to the penis has been reported to affect up to 75% of patients with ED.SELUTION SLR was awarded CE Mark Approval for the treatment of peripheral artery disease in February 2020 and for the treatment of coronary arterial disease in May 2020. The US FDA has awarded SELUTION SLR with four breakthrough designations: for the treatment of atherosclerotic lesions in native coronary arteries; coronary in-stent restenosis; peripheral below-the-knee and AV-Fistula indications.In August 2021, the first of over 3,000 patients was enrolled in a ground-breaking coronary randomized controlled study comparing SELUTION SLR with a limus drug-eluting stent [DES]. This is the largest DEB study ever initiated and has the potential to change medical practice.MedAlliance's DEB technology involves unique MicroReservoirs made from biodegradable polymer intermixed with the anti-restenotic drug sirolimus. These MicroReservoirs provide controlled and sustained release of the drug for up to 90 days1. Extended release of sirolimus from stents has been proven highly efficacious in both coronary and peripheral vasculatures. MedAlliance's proprietary CAT™ (Cell Adherent Technology) enables the MicroReservoirs to be coated onto balloons and adhere to the vessel lumen when delivered via an angioplasty balloon.Media Contact:Richard Kenyonrkenyon@medalliance.com+44 7831 569940About MedAllianceMedAlliance is a privately-owned medical technology company. It is headquartered in Nyon, Switzerland, with offices in Germany, Singapore, UK and USA. MedAlliance specializes in the development of ground-breaking technology and commercialization of advanced drug device combination products for the treatment of coronary and peripheral artery disease. For further information visit: www.medalliance.com1. Drug concentration evident in MicroReservoirs and tissue – Data on file at M.A. Med Alliance SAPhoto: https://mma.prnewswire.com/media/1895522/MedAlliance_Image.jpgLogo: https://mma.prnewswire.com/media/1196864/MedAlliance_Logo.jpg  Advertisements

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  • Where is MedAlliance's headquarters?

    MedAlliance's headquarters is located at Rue de Rive 5, Nyon.

  • What is MedAlliance's latest funding round?

    MedAlliance's latest funding round is Private Equity.

  • How much did MedAlliance raise?

    MedAlliance raised a total of $30M.

  • Who are the investors of MedAlliance?

    Investors of MedAlliance include CITIC Capital and Salubris Pharmaceuticals.

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