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massgeneralbrigham.org

Founded Year

1994

Stage

Loan - II | Alive

Total Raised

$188M

Last Raised

$30M | 2 yrs ago

About Mass General Brigham

Mass General Brigham, formerly Partners HealthCare, is a not-for-profit, integrated health care system in Boston, Massachusetts. Partners HealthCare includes community and specialty hospitals, a managed care organization, a physician network, community health centers, home care and other health related services.

Mass General Brigham Headquarter Location

399 Revolution Drive

Somerville, Massachusetts, 02145,

United States

800-856-1983

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CB Insights Intelligence Analysts have mentioned Mass General Brigham in 1 CB Insights research brief, most recently on Sep 13, 2021.

Mass General Brigham Patents

Mass General Brigham has filed 3 patents.

patents chart

Application Date

Grant Date

Title

Related Topics

Status

3/15/2013

1/10/2017

Immune system, Immunology, Clusters of differentiation, Vaccines, Autoimmune diseases

Grant

Application Date

3/15/2013

Grant Date

1/10/2017

Title

Related Topics

Immune system, Immunology, Clusters of differentiation, Vaccines, Autoimmune diseases

Status

Grant

Latest Mass General Brigham News

Wrist-worn devices are shown by mass general researchers to be cost-effective for screening of atrial fibrillation

Aug 5, 2022

A study simulating a population of 30 million people 65 and older found that wrist-wearable devices are more cost-effective than traditional electrocardiograms and pulse palpation for atrial fibrillation (AF) screening, and that they are associated with a reduction in stroke incidence Researchers believe their findings could provide a rationale for integrating wrist-worn wearables into AF screening programs for populations beginning at age 50, which is well below the typically recommended age of 65 BOSTON – Screening individuals for atrial fibrillation (AF) using wearable devices is more cost-effective than screening using conventional methods such as 12-lead electrocardiogram (ECG) and pulse palpation, or than no screening at all, researchers from Massachusetts General Hospital (MGH) have found. In a study in JAMA Health Forum, the team reported that use of contemporary wrist-worn wearables was also associated with a reduction in stroke incidence and could help to detect less frequent AF episodes through its ability to monitor for potentially irregular heart rhythm on a near-continuous basis. “The proliferation of wrist-worn devices for AF detection provides a convenient option for population-wide screening, though it’s not known if their use will lead to increased costs and problems related to follow-up testing and false positives,” says co-senior author Jagpreet Chhatwal, PhD, director of the MGH Institute for Technology Assessment. “We therefore simulated a virtual trial comparing clinical and cost outcomes under different AF screening strategies, and showed that those using wrist-worn devices generally resulted in greater benefits compared to traditional modalities, and at a cost deemed affordable to the healthcare system.” Atrial fibrillation is the most common type of heart arrhythmia, and undiagnosed AF is the leading cause of stroke. Studies have shown that population-based screening for AF could result in earlier initiation of oral anticoagulation therapy to prevent AF-related stroke, though current health system guidelines conflict. Cardiology societies in Europe and Australia/New Zealand, for example, recommend screening using pulse palpation or ECG rhythm strips (both typically conducted in physician offices) for individuals aged 65 and over, while the United States Preventive Services Task Force has concluded there is insufficient evidence to recommend AF screening using ECG. At a time when more and more consumers are adopting wearable devices, MGH researchers tested eight screening strategies – six using wrist-worn wearables and two employing pulse palpation and ECG. The six included devices using two types of technology: photoplethysmography (PPG), that is, non-invasive use of a light source at the wrist to measure changes in blood volume as an indicator of the pulse, and ECG, composed of single-lead wearables that use sensors attached to the skin to detect the electrical activity of the heart (the two technologies are often available on the same device, such as the latest iterations of Apple Watch and Fitbit). Using a model that simulates a 30-million-person cohort of people 65 and older, researchers found the “economically preferred” strategy to be wrist-wearable PPG, followed by wrist-worn ECG accompanied by a clinical-grade rhythm monitoring patch worn on the body for two weeks for confirmation. “We believe our findings provide justification for integrating wrist-worn wearables into AF screening programs, and potentially targeting populations younger than the typically recommended age of 65 for AF screening, perhaps even as low as age 50,” says co-lead author Shaan Khurshid, MD, MPH, an electrophysiology fellow at MGH. “Moreover, the ability to use these monitoring devices over extended periods could lead to the detection of infrequent paroxysmal AF, which is otherwise very difficult for clinicians to diagnose.” Adds co-senior author Steven Lubitz, MD, MPH, cardiac electrophysiologist at MGH, “Our study could potentially trigger additional research to determine how wrist-worn screening can best be deployed to improve AF-related outcomes, such as stroke prevention.” Another possible avenue of exploration is suggested by co-first author and research scientist Wanyi Chen, PhD: “If wrist-worn devices are more cost-effective, does it then make sense for insurance providers to facilitate even wider deployment by helping to defray the cost for consumers?” Chhatwal is an assistant professor of Radiology, Harvard Medical School (HMS). Lubitz is an associate professor of Medicine, HMS. The study was funded by the National Institutes of Health and the American Heart Association. About the Massachusetts General Hospital Massachusetts General Hospital, founded in 1811, is the original and largest teaching hospital of Harvard Medical School. The Mass General Research Institute conducts the largest hospital-based research program in the nation, with annual research operations of more than $1 billion and comprises more than 9,500 researchers working across more than 30 institutes, centers and departments. In July 2022, Mass General was named #8 in the U.S. News & World Report list of “America’s Best Hospitals.” MGH is a founding member of the Mass General Brigham healthcare system. Journal

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  • When was Mass General Brigham founded?

    Mass General Brigham was founded in 1994.

  • Where is Mass General Brigham's headquarters?

    Mass General Brigham's headquarters is located at 399 Revolution Drive, Somerville.

  • What is Mass General Brigham's latest funding round?

    Mass General Brigham's latest funding round is Loan - II.

  • How much did Mass General Brigham raise?

    Mass General Brigham raised a total of $188M.

  • Who are the investors of Mass General Brigham?

    Investors of Mass General Brigham include Paycheck Protection Program.

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