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Lycera

lycera.com

Founded Year

2006

Stage

Loan | Alive

Total Raised

$87.57M

Last Raised

$680K | 3 yrs ago

About Lycera

Lycera is a biopharmaceutical company pioneering approaches to the discovery and development of oral medicines for treating autoimmune diseases. The company is targeting pathways to develop new classes of selective, oral immunomodulators for the treatment of patients with diseases such as rheumatoid arthritis, psoriasis and inflammatory bowel disease. Lycera's goal is to develop drug candidates with efficacy and safety profiles that change the treatment paradigm for patients with autoimmune diseases. Based on preclinical studies, the company's emerging drug candidates demonstrate improved oral efficacy and/or safety compared to the current standard-of-care antiproliferative and immunosuppressive agents.

Headquarters Location

2800 Plymouth Road NCRC, Building 26

Ann Arbor, Michigan, 48109,

United States

734-764-4548

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Expert Collections containing Lycera

Expert Collections are analyst-curated lists that highlight the companies you need to know in the most important technology spaces.

Lycera is included in 1 Expert Collection, including Biopharma Tech.

B

Biopharma Tech

838 items

Lycera Patents

Lycera has filed 1 patent.

The 3 most popular patent topics include:

  • Transcription factors
  • Clusters of differentiation
  • Autoimmune diseases
patents chart

Application Date

Grant Date

Title

Related Topics

Status

3/9/2020

7/13/2021

Clusters of differentiation, Designer drugs, Cannabinoids, Ion channels, Monoclonal antibodies

Grant

Application Date

3/9/2020

Grant Date

7/13/2021

Title

Related Topics

Clusters of differentiation, Designer drugs, Cannabinoids, Ion channels, Monoclonal antibodies

Status

Grant

Latest Lycera News

Adjunctive Cal/BD foam treatment safe, effective option for difficult-to-treat psoriasis

Mar 21, 2022

Disclosures: Bagel reports financial relationships with AbbVie, Amgen, Arcutis Biotherapeutics, Boehringer Ingelheim, Bristol Myers Squibb, Celgene Corporation, CorEvitas LLC, Dermavant Sciences Inc., Dermira/UCB, Eli Lilly and Company, Glenmark Pharmaceuticals Ltd., Janssen Biotech, Kadmon Corporation, LEO Pharma, Lycera Corp., Menlo Therapeutics, Novartis, Pfizer, Regeneron, Sun Pharma, Taro Pharmaceutical Industries Ltd., Bausch Health Companies and Valeant Pharmaceuticals. Nelson reports no relevant financial disclosures. ADD TOPIC TO EMAIL ALERTS Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . Please try again later. If you continue to have this issue please contact customerservice@slackinc.com . Back to Healio Plaque psoriasis patients who had residual plaques following ixekizumab saw success with adjunctive calcipotriene 0.005%/betamethasone dipropionate 0.064% foam, according to a study. “Pivotal clinical trials have shown ixekizumab to be highly efficacious for the treatment of moderate to severe plaque psoriasis , with nearly 40% of patients showing complete resolution of psoriatic plaques (ie, 100% improvement in the Psoriasis Area and Severity Index) after 12 weeks of treatment. However, a considerable proportion of patients (60%-65%) continue to have residual plaques after 12 weeks of treatment,” Jerry Bagel, MD, MS, and Elise Nelson, LPN, CCRC, of the Psoriasis Treatment Center of New Jersey, wrote. This prospective, open-label, single-arm study evaluated patients at a single center who had 3% to 8% residual body surface area (BSA) involvement following ixekizumab treatment for 24 weeks or longer. The 25 enrolled patients remained on ixekizumab but were also instructed to apply a foam formulation of calcipotriene 0.005% and betamethasone dipropionate 0.064% (Cal/BD) daily for 4 weeks. Following this initial phase, patients were instructed to use the Cal/BD foam every other day through week 12. After the 4-week initial treatment phase, 56% of patients achieved the treatment goal of 1% BSA or less and 56% achieved Physician Global Assessment (PGA) scores of 1 or less. The mean BSA decreased by 55%, while the mean PGA score decreased by 49%. After 12 weeks, 64% achieved the treat-to-target goal. In addition, Dermatology Life Quality Index scores decreased by 2.3 points. “In this observational, real-world study of patients with moderate to severe plaque psoriasis, the addition of Cal/BD foam was associated with notable improvements in disease outcomes in patients who had suboptimal response after treatment with ixekizumab for [at least] 24 weeks,” the authors wrote. “Among patients with a suboptimal response to biologic therapy, adjunctive treatment with Cal/BD foam offers patients with difficult to treat psoriasis a safe and versatile treatment option, which may improve disease control and long-term management of psoriasis.” Read more about

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Lycera Frequently Asked Questions (FAQ)

  • When was Lycera founded?

    Lycera was founded in 2006.

  • Where is Lycera's headquarters?

    Lycera's headquarters is located at 2800 Plymouth Road, Ann Arbor.

  • What is Lycera's latest funding round?

    Lycera's latest funding round is Loan.

  • How much did Lycera raise?

    Lycera raised a total of $87.57M.

  • Who are the investors of Lycera?

    Investors of Lycera include Paycheck Protection Program, InterWest Partners, ARCH Venture Partners, Clarus, Third Rock Ventures and 3 more.

  • Who are Lycera's competitors?

    Competitors of Lycera include Gentronix Limited, Echelon Biosciences, Promentis Pharmaceuticals, Creabilis Therapeutics, KineMed and 13 more.

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