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KOTOBUKI Medical company logo


Founded Year



Series A | Alive

Total Raised


Last Raised

$730K | 1 yr ago

About KOTOBUKI Medical

KOTOBUKI Medical develops and manufactures surgery training equipment. The company's products include versatile training tissue (VTT), a material that can reproduce the color and shape of organs as a hygienic, easy-to-manage, and inexpensive alternative to training on animals.

Headquarters Location

190-2 Ukizuka Yashio

Saitama, 340-0835,


+81 048-951-5211

KOTOBUKI Medical's Product Videos

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KOTOBUKI Medical's Products & Differentiators


    VTT RBC TYPE is a plant-based surgical simulating organ that visualizes the thermal diffusion caused by electrocautery and ultrasonic coagulation incision devices. Its color turns white around 140℉(60℃), and it allows for more realistic training close to clinical use while being aware of the range of thermal diffusion. After turning white, it remains white even after returning to room temperature so that you can evaluate the degree of thermal diffusion after a series of training.

Expert Collections containing KOTOBUKI Medical

Expert Collections are analyst-curated lists that highlight the companies you need to know in the most important technology spaces.

KOTOBUKI Medical is included in 3 Expert Collections, including Medical Devices.


Medical Devices

8,560 items

Companies developing medical devices (per the IMDRF's definition of "medical device"). Includes software, lab-developed tests (LDTs), and combination products. *Columns updated as regularly as possible.


Education Technology (Edtech)

2,640 items


Health IT

7,901 items

KOTOBUKI Medical Patents

KOTOBUKI Medical has filed 1 patent.

The 3 most popular patent topics include:

  • Writing implements
  • Pens
  • Fountain pen and ink manufacturers
patents chart

Application Date

Grant Date


Related Topics




Writing implements, Pencils, Fountain pen and ink manufacturers, Rhodomelaceae, Buses


Application Date


Grant Date



Related Topics

Writing implements, Pencils, Fountain pen and ink manufacturers, Rhodomelaceae, Buses



Latest KOTOBUKI Medical News

08:46 EDT Study: Plant-Based Synthetic Organs Prove Effective for Fluorescence-Guided Surgical Training

Aug 3, 2022

News provided by Share this article Share this article YASHIO, Japan, Aug. 3, 2022 /PRNewswire/ -- A new study  on the effectiveness of plant-based organs for use in surgical training was performed by Dr. Naoki Nishio at the Nagoya University Graduate School of Medicine . The study was published in the Laryngoscope Investigative Otolaryngology Journal. In it, Dr. Nishio found that KOTOBUKI Medical's Versatile Training Tissue (VTT) provided a cost-effective and accurate practice model for near-infrared (NIR) fluorescence-guided tumor removal. Dr. Nakao Nishio using electrocautery on VTT tumor models. VTT is a plant-based synthetic that closely mimics human tissue. Dr. Nishio used this synthetic tissue for his paper. Near-infrared (NIR) fluorescence-guided surgery utilizes a fluorescent dye called ICG to mark tumors and lesions. This ensures a more thorough removal of cancerous tissue. Dr. Nishio conducted his study at Nagoya University's Medical xR Center. There, he and his team performed tumor enucleation and resection surgeries on VTT , a synthetic plant-based tissue created by KOTOBUKI Medical. They used NIR fluorescence-guided surgical techniques with electrocautery scalpels and ICG dye. In his study, Dr. Nishio wrote that VTT was an ideal simulator for NIR fluorescence-guided surgical training, as VTT models contain no plastics or chemicals that could create smoke when used with electrocautery scalpels. The plant-based tissue also showed the fluorescent ICG dye, as well as other models or test subjects, would. "VTT models with ICG-containing tumors could be a very useful tool for teaching surgeons how to remove the tumor by using electrocautery as 'off-the-job' training," Dr. Nishio said. This study highlights KOTOBUKI Medical's plant-based VTT models as efficient surgical simulators that create no waste and are easy to obtain. It also quantifies the effectiveness of NIR fluorescence-guided surgery as a promising method for tumor removal. About KOTOBUKI Medical KOTOBUKI Medical is a medical manufacturing company poised to introduce high-fidelity surgical simulation technology to the world. Founded in 2018, KOTOBUKI Medical aims to introduce eco-friendly and cost-effective alternatives to using animal and even human cadavers for surgical training. KOTOBUKI Medical uses patented plant-based synthetic tissue to simulate different parts of the human body. The company's Laparo Training Binder won the Good Design Award in 2018. KOTOBUKI Medical has collaborated with Jichi Medical University and the National Cancer Center Hospital East. Learn more about us at , or follow us on Twitter and TikTok. For more information, please email Erin Himeno at [email protected] or (+81) 048-951-5211. SOURCE KOTOBUKI Medical, Inc.

KOTOBUKI Medical Frequently Asked Questions (FAQ)

  • When was KOTOBUKI Medical founded?

    KOTOBUKI Medical was founded in 2018.

  • Where is KOTOBUKI Medical's headquarters?

    KOTOBUKI Medical's headquarters is located at 190-2 Ukizuka, Saitama.

  • What is KOTOBUKI Medical's latest funding round?

    KOTOBUKI Medical's latest funding round is Series A.

  • How much did KOTOBUKI Medical raise?

    KOTOBUKI Medical raised a total of $1.01M.

  • Who are the investors of KOTOBUKI Medical?

    Investors of KOTOBUKI Medical include Regional Economy Vitalization Corporation of Japan, Shinkin Capital and Gunma Regional Co-Creation Partners.

  • Who are KOTOBUKI Medical's competitors?

    Competitors of KOTOBUKI Medical include SynDaver Labs.

  • What products does KOTOBUKI Medical offer?

    KOTOBUKI Medical's products include VTT RBC TYPE and 2 more.

  • Who are KOTOBUKI Medical's customers?

    Customers of KOTOBUKI Medical include Johnson & Johnson.

Compare KOTOBUKI Medical to Competitors

SynDaver Labs Logo
SynDaver Labs

SynDaver Labs manufactures the world's most sophisticated synthetic human tissues and body parts and designs effective educational tools to teach basic science, clinical knowledge, procedural skills, teamwork, and communication skills. The company's Synthetic Human bleeds, breathes, and employs hundreds of replaceable muscles, bones, organs, veins and arteries – all made from materials that mimic the mechanical, thermal, and physicochemical properties of live tissue. This validated technology is used to replace live animals, cadavers and even human patients in medical device studies, clinical training and surgical simulation.

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