Karyopharm Therapeutics karyopharm.com


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Karyopharm Therapeutics is a clinical-stage pharmaceutical company developing small molecule modulators of nuclear transport. Karyopharm's selective inhibitors of nuclear export (SINE) function by trapping multiple tumor suppressor proteins in the nucleus, resulting in anti-cancer activity across multiple tumor types. In collaboration with many academic laboratories, SINEs targeting the major nuclear exporter XPO1 (also called CRM1) exert robust anti-cancer activity in diverse pre-clinical model...Show all

Karyopharm Therapeutics is a clinical-stage pharmaceutical company developing small molecule modulators of nuclear transport. Karyopharm's selective inhibitors of nuclear export (SINE) function by trapping multiple tumor suppressor proteins in the nu...Show all

Company (IPO / Went public)

Phone: +1 617 658 0600

Fax:

85 Wells Avenue
2/F
Newton Center, 02459
Massachusetts, United States

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Total Funding Date of Last Funding
Karyopharm Therapeutics $100.2M Nov 6, 2013

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Patents

Title Application Date Patent Date Status
(Patent / Application)
Multicyclic compounds and uses thereof Dec 29, 2016 Dec 08, 2020 Patent
Nuclear transport modulators and uses thereof Dec 30, 2016 Jul 14, 2020 Patent
Hydrazide containing nuclear transport modulators and uses thereof Nov 28, 2018 Jan 28, 2020 Patent
Nuclear transport modulators and uses thereof Dec 30, 2016 Jan 07, 2020 Patent
Polymorphs of selinexor Aug 14, 2015 Dec 31, 2019 Patent
See all 32 patents