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irxtherapeutics.com

Founded Year

1994

Stage

Acquired | Acquired

Total Raised

$153.21M

About IRX Therapeutics

IRX Therapeutics develops immune therapies to treat cancer and related diseases. The company's therapies are designed to target and restore the immune system in order to improve a patient's response to next-generation cancer vaccines and targeted therapeutics. The Company's product platform under development seeks to restore the immune system of cancer patients, which is suppressed by the onset of the disease.

IRX Therapeutics Headquarter Location

654 Madison Avenue Suite 1601

New York, New York, 10065,

United States

212-582-1199

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Expert Collections containing IRX Therapeutics

Expert Collections are analyst-curated lists that highlight the companies you need to know in the most important technology spaces.

IRX Therapeutics is included in 2 Expert Collections, including Cancer.

C

Cancer

4,784 items

Pharmaceutical and biotechnology companies with cancer therapy drug candidates.

B

Biopharma Tech

5,241 items

Companies involved in the research, development, and commercialization of chemically- or biologically-derived therapeutic & theranostic drugs. Excludes vitamins/supplements, CROs/clinical trial services.

IRX Therapeutics Patents

IRX Therapeutics has filed 16 patents.

patents chart

Application Date

Grant Date

Title

Related Topics

Status

4/13/2016

4/3/2018

Infectious causes of cancer, Papillomavirus, Gynaecological cancer, Vaccines, Immunology

Grant

Application Date

4/13/2016

Grant Date

4/3/2018

Title

Related Topics

Infectious causes of cancer, Papillomavirus, Gynaecological cancer, Vaccines, Immunology

Status

Grant

Latest IRX Therapeutics News

IRX Therapeutics acquired by Brooklyn ImmunoTherapeutics

Nov 8, 2018

IRX Therapeutics acquired by Brooklyn ImmunoTherapeutics X US-based Brooklyn ImmunoTherapeutics, a newly formed company, has acquired the assets of IRX Therapeutics for an undisclosed price. Photo: courtesy of rawpixel/Unsplash.com. Subscribe to our email newsletter This name reflects the company’s focus on advancing the science of cytokine-based immunotherapy for the treatment of a range of cancers. Brooklyn ImmunoTherapeutics general partner and board chair Charles Cherington said: “Cytokine-based immunotherapy overcomes immune suppression to activate an immune attack on tumors by upregulating multiple checkpoints and represents an exciting new approach to treating cancer. “In a Phase 2A clinical trial, IRX-2, our clinical drug candidate, demonstrated an improvement in progression free survival and overall survival in patients with head and neck squamous cell carcinoma. We believe this unique injectable cytokine mixture amplified from normal donor lymphocytes has the potential to improve patient outcomes both as a single agent and in combination with other anti-cancer agents. “We are committed to exploring this potential in a range of solid tumors including breast cancer, cervical and vulvar neoplasms, renal cell carcinoma, hepatocellular carcinoma, gastric and esophageal cancer as well as other solid tumor indications.” A global, multicenter, randomized, double-blind, placebo-controlled Phase 2B clinical trial of IRX-2 (INSPIRE trial, clinicaltrials.gov NCT02609386) in 105 patients with head and neck squamous cell carcinoma has completed enrollment with results expected in mid-2020 (CIN: NCT03267680, Breast: NCT02950259). About IRX-2 IRX-2 is a proprietary therapeutic containing numerous active cytokine components, which data suggests may restore and activate multiple immune cell types, including T cells, dendritic cells and natural killer cells, which are known to recognize and attack tumors. IRX-2 is a primary cell-derived biologic produced by stimulation of human peripheral blood mononuclear cells (PBMCs) obtained from healthy donor whole blood. Data collected to date suggest that IRX-2 reduces the immune suppression that is often seen in the cancer tumor microenvironment. This immunomodulatory activity appears to occur through the restoration of immune function and activation of a coordinated immune response against the tumor. Source: Company Press Release

  • When was IRX Therapeutics founded?

    IRX Therapeutics was founded in 1994.

  • Where is IRX Therapeutics's headquarters?

    IRX Therapeutics's headquarters is located at 654 Madison Avenue, New York.

  • What is IRX Therapeutics's latest funding round?

    IRX Therapeutics's latest funding round is Acquired.

  • How much did IRX Therapeutics raise?

    IRX Therapeutics raised a total of $153.21M.

  • Who are the investors of IRX Therapeutics?

    Investors of IRX Therapeutics include Brooklyn ImmunoTherapeutics, Halpern Denny and Co., Intervale Capital, Lilly Ventures, Novartis Venture Funds and 7 more.

  • Who are IRX Therapeutics's competitors?

    Competitors of IRX Therapeutics include Cognition Therapeutics, ViaCyte, Five Prime Therapeutics, BioNano Genomics, Terpenoid Therapeutics and 11 more.

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