Predict your next investment

Heptares Therapeutics company logo
Corporation
HEALTHCARE | Drug Discovery
heptares.com

See what CB Insights has to offer

Founded Year

2007

Stage

Corporate Minority | Alive

Total Raised

$61.17M

Last Raised

$5M | 4 yrs ago

About Heptares Therapeutics

Heptares Therapeutics focuses on the discovery and development of novel drugs acting at G-protein coupled receptors (GPCRs). Heptares StaR (Stabilized Receptor) technology enables thermo-stabilization of GPCRs, a breakthrough allowing X-ray crystallography of conformationally-constrained receptors, thereby facilitating structure-based drug design at GPCRs that have been resistant to traditional methods of drug screening.

Heptares Therapeutics Headquarter Location

BioPark, Broadwater Road Welwyn Garden City

Hertfordshire, AL7 3AX,

United Kingdom

+44 (0)1707 358 628

Latest Heptares Therapeutics News

Sosei Heptares And GSK Enter Global Collaboration And License Agreement Targeting Immune Disorders Of The Digestive System

Dec 21, 2020

Sosei Heptares And GSK Enter Global Collaboration And License Agreement Targeting Immune Disorders Of The Digestive System - Single-target agreement focused on small molecule agonists of GPR35, a genetically validated target for inflammatory bowel disease and other gastrointestinal immune disorders Author: Dec 20, 2020 7:01 PM EST TOKYO and CAMBRIDGE, England, Dec. 21, 2020 /PRNewswire/ -- Sosei Group Corporation ("the Company") (TSE: 4565) announces it has entered into a global collaboration and license agreement with GlaxoSmithKline ("GSK") [1]. The single-target agreement is focused on the discovery and development of selective, oral, small molecule agonists of GPR35, an important orphan G protein-coupled receptor (GPCR) with genetic association to inflammatory bowel disease (IBD) and other gastrointestinal immune disorders, for which there remains significant unmet need for millions of sufferers worldwide. Under the agreement, GSK licenses global rights to a portfolio of GPR35 agonists designed by Sosei Heptares using its StaR® technology and structure-based drug design (SBDD) platform. The licensed portfolio includes an advanced lead preclinical compound as well as multiple differentiated back-up compounds. Sosei Heptares and GSK will collaborate on research and early preclinical development and GSK will lead clinical development, manufacturing and commercialization. Sosei Heptares is eligible to receive an upfront payment, potential near-term development milestones and research funding of up to £34 million ( US$44 million [2]). The Company could receive additional development, regulatory and commercialization milestone payments, conditional on meeting those milestones, of up to £336 million ( US$437 million [2]). In addition, Sosei Heptares will be eligible to receive tiered, royalties on net sales of products resulting from the collaboration. Shinichi Tamura, Chairman, President and CEO of Sosei Heptares, commented: "We continue to make great progress in leveraging our unparalleled SBDD capabilities and significant investment in translational biology and therapeutic area strategies to create targeted and differentiated small molecules with potential to address clear unmet needs in gastrointestinal and immune disorders. This approach has yielded multiple opportunities for generating value through our strategy of drug discovery, early development and partnering. We are very pleased that GSK has the confidence to become our new partner on the GPR35 agonist program, which we created using this strategy. We are confident this will be a productive collaboration and that GSK's significant expertise in this important therapeutic area will support and drive the advancement of these novel agents through development." John Lepore, Senior Vice President, Research at GSK, said:"Using genetics to prioritise potential treatments for a challenging immune disorder like IBD exemplifies the approach we are taking at GSK to develop novel transformative medicines. Sosei Heptares is a world leader with an established track record in GPCR drug discovery, so we are confident in our potential to jointly identify high quality clinical candidates to deliver important new medicines for the millions of patients who are waiting." 1. Sosei Group Corporation's wholly owned subsidiary Heptares Therapeutics Ltd. entered into the agreement with GSK. 2. GBP:USD currency conversion rate: 1.3. About Sosei Heptares We are an international biopharmaceutical group focused on the discovery and early development of new medicines originating from our proprietary GPCR-targeted StaR® technology and structure-based drug design platform capabilities. We are advancing a broad and deep pipeline of novel medicines across multiple therapeutic areas, including neurology, immunology, gastroenterology and inflammatory diseases. We have established partnerships with some of the world's leading pharmaceutical companies, including AbbVie, AstraZeneca, Biohaven, Genentech (Roche), GSK, Novartis, Pfizer and Takeda and additionally with multiple emerging technology companies. Sosei Heptares is headquartered in Tokyo, Japan with corporate and R&D facilities in Cambridge, UK. "Sosei Heptares" is the corporate brand and trademark of Sosei Group Corporation, which is listed on the Tokyo Stock Exchange (ticker: 4565). Sosei, Heptares, the logo and StaR® are trademarks of Sosei Group companies. For more information, please visit https://www.soseiheptares.com .LinkedIn: @soseiheptaresco | Twitter: @soseiheptaresco | YouTube: @soseiheptaresco Enquiries: Sosei Heptares  - Media and Investor RelationsHironoshin Nomura, SVP Investor Relations and Corporate Strategy +81 (0)3 6679 2178 | Hironoshin.Nomura@SoseiHeptares.com Shinichiro Nishishita, VP Investor Relations, Head of Regulatory Disclosures +81 (0)3 5210 3399 | IR@SoseiHeptares.com Citigate Dewe Rogerson Yas Fukuda - Japanese Media +81 (0)3 4360 9234 | Yas.Fukuda@citigatedewerogerson.com Mark Swallow, David Dible - International Media +44 (0)20 7638 9571 |  SoseiHeptares@citigatedewerogerson.com Forward-looking statements This press release contains forward-looking statements, including statements about the discovery, development and commercialization of products. Various risks may cause Sosei Group Corporation's actual results to differ materially from those expressed or implied by the forward-looking statements, including: adverse results in clinical development programs; failure to obtain patent protection for inventions; commercial limitations imposed by patents owned or controlled by third parties; dependence upon strategic alliance partners to develop and commercialize products and services; difficulties or delays in obtaining regulatory approvals to market products and services resulting from development efforts; the requirement for substantial funding to conduct research and development and to expand commercialization activities; and product initiatives by competitors. As a result of these factors, prospective investors are cautioned not to rely on any forward-looking statements. We disclaim any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise. View original content: http://www.prnewswire.com/news-releases/sosei-heptares-and-gsk-enter-global-collaboration-and-license-agreement-targeting-immune-disorders-of-the-digestive-system-301196419.html

Predict your next investment

The CB Insights tech market intelligence platform analyzes millions of data points on venture capital, startups, patents , partnerships and news mentions to help you see tomorrow's opportunities, today.

Expert Collections containing Heptares Therapeutics

Expert Collections are analyst-curated lists that highlight the companies you need to know in the most important technology spaces.

Heptares Therapeutics is included in 2 Expert Collections, including Pharma Startups.

P

Pharma Startups

11,639 items

Pharmaceutical companies working across drug discovery, drug development and drug manufacturing.

B

Biopharmaceuticals

14,139 items

Companies involved in the research, development, and commercialization of chemically- or biologically-derived therapeutic & theranostic drugs. Excludes vitamins/supplements, CROs/clinical trial services.

Heptares Therapeutics Patents

Heptares Therapeutics has filed 83 patents.

The 3 most popular patent topics include:

  • G protein coupled receptors
  • Piperidines
  • Amines
patents chart

Application Date

Grant Date

Title

Related Topics

Status

5/21/2019

8/17/2021

Muscarinic antagonists, Piperidines, Amines, Quaternary ammonium compounds, G protein coupled receptors

Grant

00/00/0000

00/00/0000

Subscribe to see more

Subscribe to see more

Subscribe to see more

00/00/0000

00/00/0000

Subscribe to see more

Subscribe to see more

Subscribe to see more

00/00/0000

00/00/0000

Subscribe to see more

Subscribe to see more

Subscribe to see more

00/00/0000

00/00/0000

Subscribe to see more

Subscribe to see more

Subscribe to see more

Application Date

5/21/2019

00/00/0000

00/00/0000

00/00/0000

00/00/0000

Grant Date

8/17/2021

00/00/0000

00/00/0000

00/00/0000

00/00/0000

Title

Subscribe to see more

Subscribe to see more

Subscribe to see more

Subscribe to see more

Related Topics

Muscarinic antagonists, Piperidines, Amines, Quaternary ammonium compounds, G protein coupled receptors

Subscribe to see more

Subscribe to see more

Subscribe to see more

Subscribe to see more

Status

Grant

Subscribe to see more

Subscribe to see more

Subscribe to see more

Subscribe to see more

CB Insights uses Cookies

CBI websites generally use certain cookies to enable better interactions with our sites and services. Use of these cookies, which may be stored on your device, permits us to improve and customize your experience. You can read more about your cookie choices at our privacy policy here. By continuing to use this site you are consenting to these choices.