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helsinn.com

Founded Year

2000

Stage

Acquired | Acquired

Total Raised

$49.8M

Valuation

$0000 

About Helsinn

Helsinn is a privately owned pharmaceutical group with headquarters in Lugano, Switzerland, and operating subsidiaries in Ireland and USA. Helsinn's business model is focused on the licensing of pharmaceuticals and medical devices in therapeutic niche areas.On August 6th, 2021, Helsinn was acquired by Venture Life Group.57M.

Helsinn Headquarters Location

Via Pian Scairolo 9

Lugano, 6912,

Switzerland

+41 91 985 2121

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Expert Collections containing Helsinn

Expert Collections are analyst-curated lists that highlight the companies you need to know in the most important technology spaces.

Helsinn is included in 4 Expert Collections, including Vitamin & Supplement Startups.

V

Vitamin & Supplement Startups

237 items

M

Medical Devices

11,575 items

Companies developing medical devices (per the IMDRF's definition of "medical device"). Includes software, lab-developed tests (LDTs), and combination products. *Columns updated as regularly as possible.

B

Biopharma Tech

15,535 items

Companies involved in the research, development, and commercialization of chemically- or biologically-derived therapeutic & theranostic drugs. Excludes vitamins/supplements, CROs/clinical trial services.

H

Health IT

7,901 items

Helsinn Patents

Helsinn has filed 4 patents.

The 3 most popular patent topics include:

  • Piperazines
  • Trifluoromethyl compounds
  • Acute pain
patents chart

Application Date

Grant Date

Title

Related Topics

Status

6/8/2020

4/26/2022

Amines, Piperidines, Antiemetics, Piperazines, Trifluoromethyl compounds

Grant

Application Date

6/8/2020

Grant Date

4/26/2022

Title

Related Topics

Amines, Piperidines, Antiemetics, Piperazines, Trifluoromethyl compounds

Status

Grant

Latest Helsinn News

Weight Gain Linked to Cancer Survival in Men and Women

Sep 26, 2022

Jim Kling September 26, 2022 Cancer cachexia is a syndrome of weight loss that frequently occurs during cancer treatment. Consequences can include skeletal muscle loss, fatigue, functional impairment, worse quality of life, and worse survival. On the other hand, weight gain during cancer treatment has been tied to better survival. A new study shows that, among patients with non–small cell lung cancer (NSCLC), weight gain over the course of treatment with standard of care chemotherapy was associated with improved survival in both men and women. Few studies have examined the relationship between weight gain and outcomes by sex. “The finding that weight gain occurred in subsets of males and females is a new observation. The fact that weight gain occurs in cancer patients during anticancer treatment could confound results of clinical [trials] evaluating novel anticachexia treatments. Simultaneously studying longitudinal body weights and serum and cellular biomarkers in cancer patients might provide insights into mechanisms involved in cachexia. Increased understanding of mechanisms driving cachexia could lead to new therapeutic strategies,” said study coauthor Philip Bonomi, MD, who is an oncologist at Rush Medical College, Chicago. “This data, although it appears to be very basic, is critically important, especially as we consider our novel interventions in the treatment of cancer cachexia,” said Eric Roeland, MD, during his presentation of the study at the annual meeting of European Society for Medical Oncology. Roeland is a medical oncologist at Oregon Health & Science University, Portland. Roeland is also the lead author of cancer cachexia guidelines published by the American Society of Clinical Oncology in 2020. The guidelines suggest that dietary counseling can be offered to patients, but warns against routine use of enteral feeding tubes and parenteral nutrition. Although no specific drug can be recommended for cancer cachexia, progesterone analogs and corticosteroids used over the short term (weeks) can be used on a trial base to improve appetite and weight gain. While not approved in the United States, anamorelin was approved in 2020 in Japan for cancer cachexia in NSCLC, gastric cancer , pancreatic cancer , and colorectal cancer . The new study should raise awareness of the importance of adverse effects of cancer treatments, said Karin Jordan, MD , University Hospital Heidelberg (Germany). She served as a discussant following the presentation. “As a medical oncologist, we focus a bit too much on the benefits of antineoplastic therapy, both on cure and on the survival benefit. But what is also very, very important to do is a balanced oncology treatment to focus on the risks of oncology therapies,” she said. The study is limited by its retrospective nature and potential for bias. “The hypothesis that weight gain leads to improved survival is not really proven as it likewise may be the other way around,” Jordan said. However, in oncology research, a phenomenon called the “ obesity paradox” is increasingly catching the interest of investigators. Observational studies have shown that overweight patients with certain cancers (specifically, colorectal, endometrial and lung cancer). actually have improved overall survival as compared with normal-weight patients. Details From the New Study The researchers pooled data 1,030 patients who participated in three phase 3 clinical trials conducted between 2005 and 2011. The patients all received platinum-based chemotherapy as part of control arms. 304 were female and 726 were male. The median age was 62. 16.7% were Asian, the mean body mass index was 24.6 kg/m2, 88.5% had stage 4 disease, 36.9% had adenocarcinoma, and 86.3% were current or former smokers. Males and females had similar magnitudes and rate of weight gain over the course of treatment. Any weight gain was associated with improved overall survival in both males (12.7 vs. 8.0 months; hazard ratio, 0.60; P < .001) and females (16.2 vs. 10.1 months; HR, 0.65; P = .0028). Patients who had a weight gain of 2.5% of body weight or more saw an improvement in overall survival in both males (14.0 vs. 8.2 months; HR, 0.57; P < .001) and females (16.7 vs. 11.3 months; HR, 0.61; P = .0041). Patients with a weight gain of 5% or more was associated with improved survival in males (13.6 vs. 8.9 months; HR, 0.62; P = .0001), but there was no statistically significant association in females (16.7 vs. 12.6 months; HR, 0.69; P = .1107). Regardless of weight-gain status, males had lower survival rates than females. All of the associations were independent of smoking status. The study was funded by Pfizer. Bonomi has received honoraria from Pfizer and Helsinn for participation in scientific advisory boards. Jordan has consulted for Amgen, Hexal, Riemser, Helsinn, Voluntis, Pfizer, and BD Solution. She has received research funding from Deutsche Krebshilfe. She has received honoraria from MSD, Merck, Amgen, Hexal, Riemser, Helsinn, Voluntis, Pfizer, Pomme-med, PharmaMar, arttemoi, OnkoUpdate, Stemline, and Roche. This article originally appeared on MDedge.com , part of the Medscape Professional Network. Credits:

Helsinn Web Traffic

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  • When was Helsinn founded?

    Helsinn was founded in 2000.

  • Where is Helsinn's headquarters?

    Helsinn's headquarters is located at Via Pian Scairolo 9, Lugano.

  • What is Helsinn's latest funding round?

    Helsinn's latest funding round is Acquired.

  • How much did Helsinn raise?

    Helsinn raised a total of $49.8M.

  • Who are the investors of Helsinn?

    Investors of Helsinn include Venture Life Group, Novo Holdings, Burrill & Company, BCM Technologies, OrbiMed Advisors and 7 more.

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