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Harrington Discovery Institute

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About Harrington Discovery Institute

Harrington Discovery Institute is a project for discovery & development. The institute helps translate scientific discoveries into medicines that benefit society. The institute helps bridge the critical gap that currently exists within drug development. It is based In Cleveland, Ohio.

Headquarters Location

11407 Euclid Ave Floor 2

Cleveland, Ohio, 44106,

United States

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Latest Harrington Discovery Institute News

Cleveland Researchers Discover New Oral Drug for Lowering Cholesterol

Nov 18, 2022

Benzinga By Pr Newswire Study led by University Hospitals and Case Western Reserve University team details a small-molecule drug that lowers cholesterol by 70% in animal models CLEVELAND, Nov. 18, 2022 /PRNewswire/ -- After statins, the next leading class of medications for managing cholesterol are PCSK9 inhibitors. These highly effective agents help the body pull excess cholesterol from the blood, but unlike statins, which are available as oral agents, PCSK9 inhibitors can only be administered as shots, creating barriers to their use. AD AD Now, a new study from investigators at University Hospitals (UH) and Case Western Reserve University School of Medicine describes an orally administered small-molecule drug that reduces PCSK9 levels and lowers cholesterol in animal models by 70%. Published in Cell Reports, the findings represent a previously unrecognized strategy for managing cholesterol and may also impact cancer treatments. Cholesterol lowering is one of the most important therapies we have to prolong life and protect people from heart disease, which is still the number one cause of morbidity and mortality in the Western world, said Jonathan S. Stamler, MD, senior author, President, Harrington Discovery Institute at UH, Robert S. and Sylvia K. Reitman Family Foundation Distinguished Professor of Cardiovascular Innovation, and Professor of Medicine and Biochemistry at UH and Case Western Reserve School of Medicine.

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Harrington Discovery Institute Frequently Asked Questions (FAQ)

  • When was Harrington Discovery Institute founded?

    Harrington Discovery Institute was founded in 2012.

  • Where is Harrington Discovery Institute's headquarters?

    Harrington Discovery Institute's headquarters is located at 11407 Euclid Ave, Cleveland.

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