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Goldemberg Saladino Rolando Clerc

About Goldemberg Saladino Rolando Clerc

GSRC provides tax consulting, outsourcing, payroll, and organizational and systems consulting. It is based in Caba, Argentina.

Headquarters Location

Talcahuano 833 10th Floor

Caba, C1013,

Argentina

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Latest Goldemberg Saladino Rolando Clerc News

Gastric Signet Ring Cell Carcinoma: Current Management and Future Challenges

Sep 3, 2020

Yang Li,1 Zhikai Zhu,2 Fuhai Ma,1 Liyan Xue,3 Yantao Tian1 1Department of Pancreatic and Gastric Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China; 2School of Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China; 3Department of Pathology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China Correspondence: Yantao Tian Department of Pancreatic and Gastric Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, 17 South Panjiayuan Lane, Suite 806, Surgical Building, Chaoyang District, Beijing 100021, People’s Republic of China Tel +86 1087787120 Email tianyantao@cicams.ac.cn Abstract: Recent advances in the epidemiology, pathology, molecular mechanisms, and combined modality therapy (CMT) fields have shown that gastric signet ring cell carcinoma (GSRC) should be considered a distinct cancerous entity. Clinical management of this cancer is challenging, with chemoradioresistance and poor outcomes in advanced stages. Pathological and molecular sets of GSRC demonstrate different features of poor cohesion and differentiation according to the WHO, Japanese Gastric Cancer Association, and Laurén classifications. These features also result in poor response to adjuvant and neoadjuvant chemoradiotherapy. Certain studies of GSRC showed the disputed effectiveness of hyperthermic intraperitoneal chemotherapy and immunotherapy. Our aim was to discuss how an improved understanding of these therapeutic benefits may provide better treatment selection for patients, and therefore improve survival. The challenges in the new understanding of GSRC in routine practice and pathology, and the current limitations of treatment will also be discussed. Keywords: gastric cancer, signet ring cell, pathology, combined modality therapy This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License . By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms .

Goldemberg Saladino Rolando Clerc Frequently Asked Questions (FAQ)

  • Where is Goldemberg Saladino Rolando Clerc's headquarters?

    Goldemberg Saladino Rolando Clerc's headquarters is located at Talcahuano 833 10th Floor, Caba.

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