En Gibton

Integrated Sensor Technologies is a company that received a SBIR Phase II grant for a project entitled: Structurally Integrated Organic Light Emitting Device-Based Sensors for Dissolved Oxygen in Water. Their project aims to develop and commercialize a novel, next-generation photoluminescence (PL)-based, palm-size and miniaturizable dissolved oxygen (DO) sensor. DO sensors are primary monitors of water quality in industrial wastewater treatment. The new sensor is based on a pioneering platform for PL-based biochemical sensors where the excitation source is a pulsed organic light emitting device (OLED) pixel array that is structurally integrated with the sensor component. The individually addressable pixels and the sensor film are fabricated on either side of the glass substrate. The photodetector is "behind" the OLED array, monitoring the PL passing between the OLED pixels. This uniquely simple structural integration enables multi-sensor fabrication on a single, compact substrate, and should therefore yield field-deployable micro-sensor arrays for simultaneous detection of various analytes. This sensor has applicability in water quality measurements in wastewater treatment, power, pulp and paper, chemical, food, beverage, brewing, and pharmaceuticals plants, fish farms, fresh water, coastlines, and the oceans. Current sensors suffer from key drawbacks that limit their utility and application. Electrochemical sensors require frequent calibration and maintenance, and are typically slow to respond. PL-based sensors are expensive due to intricate design. The proposed sensor will be reliable, require very little maintenance/calibration, and will be inexpensive, with a flexible design and size. The proposed device will be uniquely simple, initially palm-size and eventually micro-size, autonomous, fast, miserly on power consumption, and inexpensive. It will be structurally integrated and will operate in a pulsed PL-lifetime mode, eliminating the need for optical components and frequent calibration. Integrated Sensor Technologies is a company that received a SBIR Phase I grant for a project entitled: Structurally Integrated Organic Light Emitting Device-Based Sensors for Dissolved Oxygen in Water. Their project aims to develop a next-generation microsensor for dissolved oxygen (DO) in water. DO sensors are a primary tool for gauging the quality of both fresh water (rivers, lakes, reservoirs) and the oceans; for monitoring the various processes in waste water treatment plants; and, for monitoring fermentation processes in the food and beverage industries. Unfortunately, electrochemical sensors are slow (response time >1 min), short-lived (a few days), and expensive (~$500). The proposed DO sensor is based on a new platform of structurally integrated photoluminescence (PL)-based chemical and biological sensors. In this platform, the pulsed light source that excites the PL is an array of individually addressable ~100 um2 to ~1 cm2 organic light-emitting device (OLED) pixels. The small pixels will eventually enable development of microsensor arrays. The ~0.5 um-thick pixel array and ~1 um-thick sensor film will be fabricated on opposite sides of a glass or plastic substrate, or on two substrates attached back-to-back. The Si photodiode will be "behind" the OLED array, monitoring the PL passing between the OLED pixels. This uniquely simple structurally integrated platform should ultimately yield multianalyte chemical and biological microsensor arrays for a wide variety of agents. If successful the proposed device will be uniquely simple, initially palm-size and eventually microsize, autonomous, fast (~1 sec response), miserly on power consumption, and inexpensive (ultimately with an essentially disposable OLED/sensor film module). It will operate in the PL-lifetime mode, eliminating the need for frequent calibration. It will consequently replace the short-lived electrochemical sensors and the expensive PL-based DO sensors that currently serve the diverse markets listed above. The proposed development of the DO microsensor will demonstrate the viability of the new OLED-based sensor platform, leading the way towards the development of multianalyte chemical and biological microsensor arrays for gas and liquid phases. This development will enhance scientific and technological needs in the field of sensor technology by addressing current issues of sensor size, cost, analyte sampling, and field deployability.

Laureate Pharma, Inc. is a full service contract manufacturing organization(CMO) providing development and cGMP manufacturing services in the company's FDA registered facilities in Princeton, New Jersey. The company is dedicated to supporting the development and commercialization of biopharmaceutical, drug and diagnostic products for pharmaceutical, diagnostic and biotech companies.The company aims to provide a range of product development and manufacturing services from cell line optimization and process design to development of full-scale cGMP protein production, purification and aseptic filling, in addition to corresponding testing, validation, analytical and regulatory support. The company's focus is on mammalian cell based monoclonal antibody and recombinant protein production for clinical and modest commercial supply.The company view the company's customers as partners and provide them with flexible solutions that reduce time to clinic and market. Focused on operational excellence, the company's highly experienced staff works with the company's customers to improve the quality of their products and processes.The company value the company's customers, stakeholders and associates. Therefore, the company measure the company's success by meeting the company's customers' needs, generating results in terms of quality, timeliness and on budget performance, as well as fostering an environment of trust, growth and diversity for the company's team.

Blaze Systems is a provider of total LIMS software solutions for the laboratory marketplace.

Kryosphere provides customized biorepository, logistical, and clinical sample management services to companies with a critical biospecimen component. Kryosphere delivers secure, scalable solutions to customers ranging from small, emerging entities to large corporations worldwide.

Central Washington Biodiesel (CWBiodiesel) is producing 100% Washington biodiesel using only Washington grown and processed vegetable oil.

Critical Biologics Corporation (CBC), based in Cambridge, MA, is a small biotechnology company committed to making available products to address the many unmet medical needs in Critical Care Medicine. The company believe that the traditional commercial approach of targeting a single facet of a therapydrug, device, diagnostic, or monitor ignores the fact that often these modalities are employed together by Intensivists to treat the increasing complex diseases of their patients.