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dicerna.com

Founded Year

2007

Stage

Take Private | Alive

Total Raised

$123.8M

Valuation

$0000 

Revenue

$0000 

About Dicerna Pharmaceuticals

Dicerna Pharmaceuticals is a pharmaceutical company developing RNA interference (RNAi)-based therapeutics against genetically-defined targets in multiple disease areas, including cancer. Dicerna's therapeutic approach utilizes its Dicer Substrate siRNA (DsiRNA) molecules and EnCore drug delivery technologies to silence previously undruggable disease targets, offering a potential new treatment option for patients. Dicerna delivers its DsiRNA molecules to cancer cells using its EnCore lipid nanoparticle drug delivery technology. EnCore has been specifically engineered to accumulate in tumors and mediate efficient delivery of the DsiRNAs to the RNAi machinery in the cancer cell cytoplasm. Encore particles are well tolerated and manufactured using well-established unit operations to ensure commercial scalability.

Dicerna Pharmaceuticals Headquarter Location

480 Arsenal St Building 1, Suite 120

Watertown, Massachusetts, 02472,

United States

617-621-8097

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Expert Collections containing Dicerna Pharmaceuticals

Expert Collections are analyst-curated lists that highlight the companies you need to know in the most important technology spaces.

Dicerna Pharmaceuticals is included in 4 Expert Collections, including Cancer.

C

Cancer

4,784 items

Pharmaceutical and biotechnology companies with cancer therapy drug candidates.

R

Regenerative Medicine

1,818 items

Regenerative medicine refers to the process of activating, replacing, engineering or regenerating human genetic material, cells, tissues or organs to restore normal function. It also includes bioengineered tissues used for in vitro testing (e.g. organ-on-a-chip, organoids).

B

Biopharma Tech

15,535 items

Companies involved in the research, development, and commercialization of chemically- or biologically-derived therapeutic & theranostic drugs. Excludes vitamins/supplements, CROs/clinical trial services.

D

Diabetes

1,750 items

Dicerna Pharmaceuticals Patents

Dicerna Pharmaceuticals has filed 72 patents.

The 3 most popular patent topics include:

  • Molecular biology
  • RNA
  • MicroRNA
patents chart

Application Date

Grant Date

Title

Related Topics

Status

9/10/2021

4/26/2022

MicroRNA, RNA, Molecular biology, Hepatology, Gene expression

Grant

Application Date

9/10/2021

Grant Date

4/26/2022

Title

Related Topics

MicroRNA, RNA, Molecular biology, Hepatology, Gene expression

Status

Grant

Latest Dicerna Pharmaceuticals News

PepGen Continues to Build Leadership Team with Additions of Senior Vice President, Clinical Operations and Vice President, Toxicology

Mar 30, 2022

Boston, Massachusetts, UNITED STATES BOSTON, March 30, 2022 (GLOBE NEWSWIRE) -- PepGen, Inc., advancing the next generation of oligonucleotide therapies with the goal of transforming the treatment of severe neuromuscular and neurologic diseases, today announced that it has appointed Jennifer Cormier as Senior Vice President, Clinical Operations and Dr. Jeffrey Foy as Vice President, Toxicology. Ms. Cormier brings over 15 years of experience in therapeutic and medical device development to the PepGen team, and in her new role will lead clinical operations across the company’s pipeline of Enhanced Delivery Oligonucleotide (EDO) therapeutics, including PGN-EDO51, PepGen’s clinical-stage product candidate for the treatment of Duchenne muscular dystrophy. With over 20 years of experience in the pharmaceutical industry, Dr. Foy brings deep expertise in the toxicology of oligonucleotide and peptide therapeutics to PepGen, and will facilitate the company’s efforts to discover, develop and translate EDO product candidates. “Jennifer and Jeff bring a wealth of experience in the development of transformative therapeutics to our team, and both will be instrumental in advancing our portfolio of EDO programs for patients with deep unmet need,” said James McArthur, Ph.D., President and Chief Executive Officer of PepGen. “Following Health Canada’s recent acceptance of our Clinical Trial Application (CTA) for PGN-EDO51, and the initiation of our first-in-human clinical trial for this product candidate expected in the next month, Jennifer and Jeff will play a critical role in enabling our clinical-stage operations, and in preparing our pipeline therapeutics for future clinical trials.” Ms. Cormier has led a number of clinical-stage programs across the course of her career, ranging from first-in-human trials through to post-marketing approval studies in a variety of therapeutic areas, including rare genetic diseases, women’s health, Parkinson’s disease, diabetes and obesity, and major depressive disorder. Prior to joining PepGen, Ms. Cormier served as Vice President of Clinical Operations at Relmada Therapeutics, where she was responsible for oversight and execution of late-phase clinical programs. She has also held leadership roles at Sojournix, Acorda Therapeutics, GI Dynamics and Shire. She earned her Bachelor of Science degree in Biology from the University of Massachusetts in Boston. Ms. Cormier added, “I am honored to be joining the PepGen team, which has a diversity of talent and expertise that is truly unique. PepGen’s leadership shares my own passion for developing therapies that have the potential to improve therapeutic outcomes for people living with rare diseases. Their purposeful focus on that mission is inspiring, and serves as a constant source of motivation as we drive our programs forward into clinical trials.” Dr. Foy previously served as the Executive Director of Toxicology at Dicerna Pharmaceuticals, where he designed and executed nonclinical safety pharmacology and toxicology studies for internal and partnered development assets. Prior to his time at Dicerna, he held various leadership positions at Celgene, where he worked across a number of therapeutic areas, including oncology, inflammation and immunology. Dr. Foy has made broad contributions to our understanding of the toxicology of oligonucleotide and peptide therapeutics, and his work has been cited in numerous peer-reviewed publications and presentations. He is a Diplomate of the American Board of Toxicology, a member of the Oligonucleotide Therapeutics Society, and Chair of the Oligonucleotide Safety Working Group. Dr. Foy received his Ph.D. in Toxicology from Northeastern University in Boston after obtaining his Bachelor of Science in Biological Sciences at the University of Vermont. “I am delighted to have joined such an amazing team at PepGen. Our programs have tremendous potential to make a meaningful impact in the lives of patients with rare neuromuscular diseases, including Duchenne muscular dystrophy and myotonic dystrophy type 1, and I look forward to contributing to the continued progress of our EDO programs,” said Dr. Foy. About PepGen PepGen, Inc. is a biotechnology company advancing next-generation oligonucleotide therapies for neuromuscular and neurologic diseases. PepGen’s proprietary Enhanced Delivery Oligonucleotides (EDOs) are designed to target the underlying causes of rare diseases, such as Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1), in a safe and effective manner. In preclinical studies, PepGen’s enhanced delivery peptides demonstrated highly effective cell penetration and delivery of therapeutic candidates to multiple tissue types, including cardiac tissue. PepGen was founded by leading neuromuscular and neurology researchers in Oxford and Cambridge, UK, and is backed by a strong syndicate of investors including RA Capital Management, Oxford Science Enterprises, and others. The company is headquartered in Boston, Mass. For more information, visit  www.pepgen.com or follow PepGen on  Twitter   and  LinkedIn . Media Contact

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  • When was Dicerna Pharmaceuticals founded?

    Dicerna Pharmaceuticals was founded in 2007.

  • Where is Dicerna Pharmaceuticals's headquarters?

    Dicerna Pharmaceuticals's headquarters is located at 480 Arsenal St, Watertown.

  • What is Dicerna Pharmaceuticals's latest funding round?

    Dicerna Pharmaceuticals's latest funding round is Take Private.

  • How much did Dicerna Pharmaceuticals raise?

    Dicerna Pharmaceuticals raised a total of $123.8M.

  • Who are Dicerna Pharmaceuticals's competitors?

    Competitors of Dicerna Pharmaceuticals include Sirnaomics, Oxford BioMedica, Cell Point, Agrisoma BioSciences, PhaseRx, KemPharm, Bar Harbor BioTechnology, Vascular Biogenics, Calibrant Biosystems, Advanced Cell Technology and 12 more.

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