Predict your next investment

Coagulo company logo
HEALTHCARE | Medical Devices & Equipment / Imaging & Diagnostic Equipment
coagulomed.com

See what CB Insights has to offer

Founded Year

2019

Stage

Seed VC | Alive

Total Raised

$6.5M

Last Raised

$6.5M | 7 mos ago

About Coagulo

Coagulo develops rapid, ultra-portable and comprehensive diagnostics for the personalized diagnosis and management of all coagulation-related diseases.

Coagulo Headquarter Location

2000 Commonwealth Ave Suite 2000

Auburndale, Massachusetts, 02466,

United States

Latest Coagulo News

Coagulo nabs $6.5M in new financing for blood clotting diagnostics platform

Dec 30, 2020

December 29, 2020 Coagulo Medical Technologies Inc. raised $6.5 million in financing to accelerate delivery of its precision-medicine coagulation diagnostics platform. 20/20 Healthcare Partners led the investment with participation from Sands Capital, Good Growth Capital, IAG Capital Partners, and private investors. The company also received funding through a Small Business Innovation Research (SBIR) grant from the National Science Foundation to develop a COVID-19-related coagulation test. “Coagulo has developed a platform that directly responds to current medical needs and, further, will support traditional tests like prothrombin time and activated partial thromboplastin time,” said Hillel Bachrach, managing partner of 20/20 Healthcare Partners. “We are excited to invest in Coagulo and to help accelerate their path to market as they up-end an industry that has seen very little innovation for decades.” The company is completing the final phase of development of the platform and actively engaged in discussions with the U.S. FDA in anticipation of clinical trials. The new funds will support further expansion of the platform’s capabilities. “This funding will also continue to support multiple, ongoing collaborations with leading institutions across the country. These collaborations have generated a significant amount of clinical data ahead of our pivotal study for submission to FDA,” Coagulo’s Chairman and CEO Jarrod Niebloom told BioWorld. The last substantial advance in coagulation testing methods occurred more than 50 years ago and provides general information on blood clotting function without specifying the cause. In contrast, Coagulo’s technology can identify coagulation factor-specific deficiencies, inhibition and abnormalities and quantify the effect on coagulation. Coagulo’s point-of-care device delivers actionable information in 10 minutes from a few drops of blood. Powered by artificial intelligence, the platform combines more than 20 tests to analyze the entire coagulation cascade in one pass. That allows it to be used for personalized and rapid diagnosis and management of any coagulation disorder and enables it to identify the use, type, and current effect of any anticoagulant, even on patients unable to communicate their medical history. “This is a huge advancement over traditional coagulation tests – like prothrombin time (PT/INR) and activated partial thromboplastin time (aPTT) – which are only capable of indicating whether a clotting problem is a result of a problem in the intrinsic or extrinsic pathway. We can actually home in on which particular factor is aberrant,” Niebloom explained. The Cambridge, Mass.-based startup operates out of Alexandria Launchlabs and licensed technology from the Massachusetts Institute of Technology (MIT) and Massachusetts General Hospital. Coagulo’s platform combines patent-pending assays, innovative microfluidic technology, proprietary data analytics and digital connectivity. COVID connection Excess clotting emerged as an unexpectedly common symptom of COVID-19, contributing significantly to organ failure and death early in the pandemic. Inflammation and coagulation each further activate the other, complicating treatment in patients with serious disease. Coagulo is working with hospitals to better understand the mechanisms of thrombosis in patients infected with SARS-CoV-2 and to develop optimal treatments for those needing complex coagulation management. Clarification of the cause and effects of thrombosis in these patients is urgently needed as current anticoagulation recommendations vary in what to administer, when to start therapy, how much to administer, and the monitoring required. Coagulo could play a significant role in identifying the factors driving increased clotting, which may differ from person to person. “We are assessing our technology’s ability to evaluate the effect of various anticoagulants on patients with COVID-19, quantify anticoagulation levels and detect the presence of prothrombotic phenotypes,” Niebloom said. Anticoagulant identification More than 10 million people in the U.S. use anticoagulants to manage a range of conditions such as atrial fibrillation, autoimmune disorders, COVID-19, cancer, and joint replacement surgery, among others. Anticoagulants are also the leading cause of drug-related adverse events and associated hospitalizations. Hospitalizations related to the drugs themselves or to trauma are often complicated by difficulty determining how much anticoagulant effect remains in the patient’s system. For patients who are unconscious or otherwise unable to communicate whether they take an anticoagulant and, if so, which one, knowing how and when to proceed safely can be tricky. No FDA-approved test can identify the five commonly used direct-acting oral anticoagulants (DOACs) – apixaban, dabigatran, rivaroxaban, edoxaban, and betrixaban – from a blood sample. Dabigatran, a direct thrombin or factor IIa inhibitor, requires a different reversal agent than the other four, which are all factor Xa inhibitors. In a 100-patient clinical study conducted at MGH Emergency Department, Coagulo identified patients on DAOCs with 100% specificity and more than 95% sensitivity. It can also detect the reversal of anticoagulation.

Predict your next investment

The CB Insights tech market intelligence platform analyzes millions of data points on venture capital, startups, patents , partnerships and news mentions to help you see tomorrow's opportunities, today.

Expert Collections containing Coagulo

Expert Collections are analyst-curated lists that highlight the companies you need to know in the most important technology spaces.

Coagulo is included in 2 Expert Collections, including Medical Devices.

M

Medical Devices

8,341 items

Companies developing medical devices (per the IMDRF's definition of "medical device"). Includes software, lab-developed tests (LDTs), and combination products. *Columns updated as regularly as possible.

H

Health & Wellness Assessment Tools

2,094 items

Companies developing or offering products that aid in the assessment, screening, diagnosis, or monitoring of a person's state of health/wellness. Excludes providers.

Coagulo Web Traffic

Rank
Page Views per User (PVPU)
Page Views per Million (PVPM)
Reach per Million (RPM)
CBI Logo

Coagulo Rank

CB Insights uses Cookies

CBI websites generally use certain cookies to enable better interactions with our sites and services. Use of these cookies, which may be stored on your device, permits us to improve and customize your experience. You can read more about your cookie choices at our privacy policy here. By continuing to use this site you are consenting to these choices.