Cleave Biosciences cleavebio.com


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Cleave Biosciences develops drugs that target protein homeostasis systems and improve the treatment of solid tumors and hematologic malignancies. The company's CB-5083 is an oral inhibitor of p97, a critical enzyme that controls various aspects of protein homeostasis and has the potential to treat a wide range of cancers, including both solid tumors and hematologic malignancies.

Cleave Biosciences develops drugs that target protein homeostasis systems and improve the treatment of solid tumors and hematologic malignancies. The company's CB-5083 is an oral inhibitor of p97, a critical enzyme that controls various aspects of pr...Show all

Company (Alive / Active)

Phone: 650-443-3000

Fax:

866 Malcolm Road
Suite 100
Burlingame, 94010
California, United States

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Total Funding Date of Last Funding
Cleave Biosciences $91M Aug 8, 2016

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Investors

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Patents

Title Application Date Patent Date Status
(Patent / Application)
Monocyclic pyrimidine/pyridine compounds as inhibitors of p97 complex Dec 10, 2014 Jan 16, 2018 Patent
Fused pyrimidines as inhibitors of p97 complex Jan 19, 2015 Nov 28, 2017 Patent
Fused pyrimidines as inhibitors of p97 complex Jul 19, 2013 Oct 25, 2016 Patent
Fused pyrimidines and substituted quinazolines as inhibitors of p97 Jul 19, 2013 Jun 23, 2015 Patent
Methods and compositions for inhibition of the transitional endoplasmic reticulum atpase May 06, 2011 Oct 21, 2014 Patent
See all 11 patents