Aridhia Informatics to manage data on new Alzheimer’s study
13:54, 22 Aug 2016
The £6.9m Deep and Frequent Phenotyping study will be the most rigorous series of tests ever performed on volunteers to detect Alzheimer’s disease
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Software developer Aridhia Informatics has been selected to work on a new study which aims to improve detection of Alzheimer’s Dementia. The £6.9 million Deep and Frequent Phenotyping study will be the most rigorous series of tests ever performed on volunteers to detect Alzheimer’s disease. The study is being funded by the National Institute of Health Research (NIHR) and the Medical Research Council (MRC). Aridhia, a spin out from the University of Dundee, has developed a cloud-based data analysis platform to process and manage clinical and research informatics between organisations and across geographies. Aridhia will provide data analytics using its AnalytiXagility platform to help researchers analyse data gathered from 250 volunteers recruited from existing study cohorts led by the Dementias Platform UK. The Aridhia technology will also be made accessible to members of the multi-site team, which includes researchers at Edinburgh University, Oxford University and the Alzheimer’s Society. The study is designed to identify measureable characteristics, known as biomarkers, which can detect Alzheimer’s disease at an early stage, even when the person has displayed no obvious symptoms. The tests will include wearable devices which will provide researchers with detailed information on the wearer's movement and gait, and sophisticated retinal imaging to detect subtle changes affecting central and peripheral vision. Aridhia chief executive Chris Roche said: “Alzheimer’s dementia is a brutally progressive disease, for which we have no cure. “It is crucial that we gain a better understanding of the early stages, to help us discover which treatments can slow down or even stop the symptoms. “AnalytiXagility will help researchers to faster identify biomarkers, which will allow them to speed up the clinical trial process and find out which drugs are effective, and which ones are not. “This will ensure patients will benefit from the research more quickly, and also helps to streamline the process to make it more cost-effective.”
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Aridhia Informatics to manage data on new Alzheimer’s study

Aridhia Informatics reports retained loss of £3.3m
Aridhia Informatics reports retained loss of £3.3m
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Aridhia Informatics has recorded a retained loss of more than £3.3 million in its most recent financial year. The Edinburgh healthcare analytics firm, founded by entrepreneur David Sibbald, declined to comment on the reasons for the loss. The abbreviated balance sheet in annual accounts filed at Companies Accounts shows its net assets were valued at close to £1.6m in 2014, down from £2.9m in the prior year. Loading article content
Aridhia, founded in 2007, has received backing from the likes of Scottish Equity Partners and Albion Ventures. Its software allows large amounts of healthcare data to be analysed in ways which can help to support treatment of patients. Share article
Customers include NHS Scotland and it has also partnered with Craneware to start selling products in the United States. Mr Sibbald, 55, previously built up software firm Atlantech Technologies until it was sold to Cisco for £113m in 2000. Promoted Stories


Aridhia Informatics reports retained loss of £3.3m

Deputy Business Editor
Tuesday 22 July 2014
HEALTH data analytics firm Aridhia Informatics has seen its losses widen from £1.5 million to £3.5 million after a period of heavy investment which saw its staff numbers more than double. HEALTH data analytics firm Aridhia Informatics has seen its losses widen from £1.5 million to £3.5 million after a period of heavy investment which saw its staff numbers more than double. Custom byline text: 
Greig cameron DEPUTY BUSINESS EDITOR
Revenue was said to have increased from £2.5 million to more than £3 million in 2013 but operating costs surged as staff numbers rose to 65, up from around 30 at the start of the previous calendar year. Loading article content
However chief financial officer David Allan said the results were in line with expectations and the company remained very optimistic about the long term potential of its products. He said: "We invested fairly heavily in the second half of 2012 and those costs really hit for the full year in 2013 for the first time. "It has all been in line with the business plan and the expectations. "The investment has been heavy as we have built a collaborative data analytics platform. "
Edinburgh-based Aridhia is headed by entrepreneur David Sibbald and its backers include the likes of Scottish Equity Partners and Albion Ventures. The software platform developed by Aridhia allows large amounts of health data to be analysed to help support treatment of patients. Mr Allan said: "The potential for the business is still enormous because of the issues within the healthcare market and even more the genomic, personal medicine. "We are not unhappy with where the business is at the moment. "
Mr Allan said the business anticipated being in profit next year and forecast rising revenues. He added Aridhia was still making a lot of investment in further product development and building up its sales team. Commenting & Moderation
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Aridhia sees losses swell from £1.5m up to £3.5m

Group Business Editor
Thursday 8 May 2014
SCOTTISH entrepreneur David Sibbald's Aridhia Informatics venture has been successful in a UK-Government-led competition to accelerate the development of data management and analytical techniques that will help deliver genomic medicine within the National Health Service in England. SCOTTISH entrepreneur David Sibbald's Aridhia Informatics venture has been successful in a UK-Government-led competition to accelerate the development of data management and analytical techniques that will help deliver genomic medicine within the National Health Service in England. Custom byline text: 
ian Mcconnell business editor
Edinburgh-based Aridhia, which has created a software platform to enable analysis of large amounts of health-related data to support treatment of patients, announced yesterday that it had won funding in a Small Business Research Initiative competition led by Genomics England, a company set up by the Department of Health. Loading article content
Aridhia noted the objective of the competition had been to discover innovative technologies that would address the requirements of Genomics England's 100,000 Genomes Project and demonstrate the solution could provide the NHS with meaningful and actionable data based on patients' genetic material. It highlighted the goal of making these data a routine part of clinical decision-making. Aridhia said its bid had focused on the scale and accuracy of the analytics required to deliver genomic medicine as a routine service by enabling the "industrialisation" of multiple annotation pipelines from different genomic sequence and bio-informatics providers. It added that if healthcare and research organisations were to deliver on the promise of genomic medicine, this would require considerable developments around the integration, clinical validation and curation of large-scale clinical and genomic data-sets. Aridhia said the Department of Health was investing up to £10m in total in the competition, managed by Genomics England. A spokeswoman noted Aridhia was one of eight winners, and said the company would use funding from phase one of the competition to demonstrate the technical feasibility of its innovative proposals that would help to treat rare diseases and cancer. Genomics England was set up to deliver the 100,000 Genomes Project, announced by Prime Minister David Cameron in December 2012. This project aims to sequence 100,000 personal DNA codes of patients over five years. Genomics England says on its website that this "unrivalled knowledge" will help doctors' understanding, leading to better and earlier diagnosis and personalised care. It adds that, based on expert scientific advice, it will start by tackling cancer, rare diseases and infectious diseases. Aridhia said its ground-breaking work would be carried out at the Stratified Medicine Scotland Innovation Centre, in Glasgow, on AnalytiXagility, the recently launched healthcare and research data science platform developed by the Scottish company. Aridhia is leading a consortium of specialists, including Fios Genomics, EMC and Pivotal, in this project. Mr Sibbald, chief executive of Aridhia, said: "Clinical interpretation of sequence data can inform likely disease progression, prognosis and can identify potential response to treatment. Ultimately, this could lead to improved treatment success rates and reduce unnecessary side-effects. "One of the key challenges is the availability of industrial-strength annotation pipelines that can be deployed at scale and integrated effectively with a range of other data associated with patient care and treatment. "
Aridhia said the ultimate aim was to identify the best way to present data to clinicians in an easily interpreted format, giving the NHS access to clinically relevant, actionable information which could be used to influence patient care directly. The Scottish company, which works internationally on chronic disease management projects and is active in Kuwait, Australia and Scotland, employs 90 staff, including clinicians, life scientists, computer scientists, and data scientists. It has annual revenues of £3m, and works with governments, health organisations and chronic disease charities. Aridhia's customer base includes NHS Scotland, which has been using the company's software platform to help track the treatment of cancer patients and to analyse data relating to patients who are on complex mixes of medication for multiple chronic conditions. Commenting & Moderation
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Aridhia Informatics wins funding in genomic medicine drive

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Aridhia Informatics is focused in the management of chronic diseases, stratified medicine and biomedical research through the use of biomedical informatics and analytics. Aridhia believes that the integration and application of patient, clinical and genomic data represents a powerful opportunity to support clinical care across healthcare sectors, provide patients with the ability to take a more active role in their own care and provide information at a population level about disease trends, risk factors, impact of treatment and informed public health programs. Working in close collaboration with experts in a clinical faculty model, Aridhia's multidisciplinary team provides a unique combination of expertise to address one of the world's most pressing health problems.

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