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Aquinox Pharmaceuticals

aqxpharma.com

Founded Year

2004

Stage

Acq - P2P | Acquired

Total Raised

$65.84M

Valuation

$0000 

About Aquinox Pharmaceuticals

Aquinox Pharmaceuticals (NASDAQ: AQXP) is a pharmaceutical company discovering and developing drug candidates to treat inflammation, inflammatory pain, and blood cancers. The company is dedicated to advancing therapeutics that it believes will make a clinically meaningful difference in patients' lives.

Headquarters Location

Suite 450 – 887 Great Northern Way

Vancouver, British Columbia, V5T 4T5,

Canada

604-629-9223

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Expert Collections containing Aquinox Pharmaceuticals

Expert Collections are analyst-curated lists that highlight the companies you need to know in the most important technology spaces.

Aquinox Pharmaceuticals is included in 2 Expert Collections, including Cancer.

C

Cancer

3,605 items

Companies researching, developing, or offering products & services that aid in the screening, prevention, diagnosis, management, and treatment of cancer.

B

Biopharma Tech

15,535 items

Companies involved in the research, development, and commercialization of chemically- or biologically-derived therapeutic & theranostic drugs. Excludes vitamins/supplements, CROs/clinical trial services.

Aquinox Pharmaceuticals Patents

Aquinox Pharmaceuticals has filed 1 patent.

The 3 most popular patent topics include:

  • Amines
  • Clusters of differentiation
  • Inflammations
patents chart

Application Date

Grant Date

Title

Related Topics

Status

4/5/2019

8/23/2022

Analgesics, Clusters of differentiation, Inflammations, Amines, H1 receptor antagonists

Grant

Application Date

4/5/2019

Grant Date

8/23/2022

Title

Related Topics

Analgesics, Clusters of differentiation, Inflammations, Amines, H1 receptor antagonists

Status

Grant

Latest Aquinox Pharmaceuticals News

Orum Therapeutics Appoints David Main to Board of Directors

Mar 23, 2022

March 23, 2022 08:00 AM Eastern Daylight Time BOSTON & DAEJEON, South Korea--( BUSINESS WIRE )-- Orum Therapeutics , a biotechnology company pioneering the development of tumor-directed targeted protein degraders to treat cancer, today announced the appointment of David Main to the Company’s Board of Directors. Mr. Main is a highly experienced biopharmaceutical executive who has more than 30 years of industry leadership experience with a strong track record of value creation and company growth. “David has extensive experience financing and leading biotech companies from early-stage research through commercial readiness,” said Sung Joo Lee, Ph.D., Founder and CEO of Orum Therapeutics. “I welcome David’s insight as Orum advances into clinical trials the Company’s first-in-class therapeutic candidates based on our Antibody neoDegrader Conjugate platform.” Orum’s Antibody neoDegrader Conjugate (AnDCTM) platform is built on novel targeted protein degrader (TPD) combined with the precise tumor cell delivery mechanisms of antibodies to generate innovative, first-in-class cell-specific TPD for the treatment of cancer. The company has developed new molecular glue degrader payloads (neoDegraders) to specifically degrade an intracellular target protein within cancer cells via the E3 ubiquitin ligase pathway. Conjugated to antibodies, neoDegraders are designed to be delivered specifically to cancer cells and degrade the intracellular target protein and cause tumor cell death. “Orum’s AnDC platform combines the strengths of targeted protein degraders and antibody drug conjugates with a diversity of payloads needed to deliver precise tumor-killing action,” said Mr. Main. “I look forward to working with the Orum team and Board as the Company advances these innovative first-in-class tumor-directed targeted protein degraders into the clinic to improve the treatment of cancer.” The lead therapeutic programs from Orum’s AnDC platform are ORM-5029 and ORM-6151, potential first-in-class targeted protein degrader therapies for HER2-expressing breast cancer and CD33-positive acute myeloid leukemia (AML), respectively. Each program employs a different antibody drug to specifically deliver Orum’s lead neoDegrader to tumor cells. The company plans to file Investigational New Drug (IND) applications with the U.S. Food and Drug Administration (FDA) for ORM-5029 in 2022 and ORM-6151 in 2023. Mr. Main is President and Chief Executive Officer of Notch Therapeutics. Previously, as Chairman and CEO of Aquinox Pharmaceuticals, a company he co-founded in 2006, Mr. Main oversaw the advancement of the company’s lead product from target validation through Phase 3 clinical trials. He also led the transition of Aquinox from a private company to a Nasdaq-listed public company with approximately $300 million raised in equity capital and then completed the successful merger of Aquinox with Neoleukin Therapeutics. Prior to his leadership of Aquinox, Mr. Main served as President and CEO of INEX Pharmaceuticals and as a Vice President of QLT. He formerly served as the Chair of LifeSciences BC (formerly BC Biotech), BIOTECanada, and Accel-Rx as well as a Director of BIO.org. Mr. Main began his career as a licensed pharmacist at the Royal Columbian Hospital in New Westminster, B.C. He received a BSc in pharmacy and an MBA from the University of British Columbia. About Orum Therapeutics Orum Therapeutics is pioneering the development of tumor-directed targeted protein degraders by leveraging its TPD2™ approach to provide dual precision, antibody-enabled targeted protein degraders for cell-specific delivery. The Company’s proprietary platforms generated using the TPD2 approach includes the Antibody neoDegrader Conjugate (AnDC™) platform, which generates first-in-class antibody drug conjugates. The first therapeutic candidates from the AnDC platform are in development for the treatment of solid tumors and hematologic cancers. Orum is located in Cambridge, Massachusetts, and Daejeon, South Korea. For more information, visit www.orumrx.com . Contacts

Aquinox Pharmaceuticals Frequently Asked Questions (FAQ)

  • When was Aquinox Pharmaceuticals founded?

    Aquinox Pharmaceuticals was founded in 2004.

  • Where is Aquinox Pharmaceuticals's headquarters?

    Aquinox Pharmaceuticals's headquarters is located at Suite 450 – 887 Great Northern Way, Vancouver.

  • What is Aquinox Pharmaceuticals's latest funding round?

    Aquinox Pharmaceuticals's latest funding round is Acq - P2P.

  • How much did Aquinox Pharmaceuticals raise?

    Aquinox Pharmaceuticals raised a total of $65.84M.

  • Who are the investors of Aquinox Pharmaceuticals?

    Investors of Aquinox Pharmaceuticals include Sun Pharma, Ventures West, Johnson & Johnson Innovation, Pfizer Venture Investments, Baker Brothers Investments and 4 more.

  • Who are Aquinox Pharmaceuticals's competitors?

    Competitors of Aquinox Pharmaceuticals include Humanetics, Cornerstone Pharmaceuticals, Neos Therapeutics, Catabasis Pharmaceuticals, Kereos, CoImmune, Bexion Pharmaceuticals, PNP Therapeutics, Deciphera Pharmaceuticals, Akebia Therapeutics and 49 more.

Compare Aquinox Pharmaceuticals to Competitors

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Inimex Pharmaceuticals

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Cylene Pharmaceuticals

Cylene Pharmaceuticals is a clinical-stage, private company developing small molecule drugs against newly validated cancer targets. Cylene has taken a position in the discovery and development of first-in-class cancer drugs that activate the p53 tumor suppressor and drugs that target the CK2 protein kinase. The Company's p53 Activator/Pol I program delivered CX-5461, a Phase I stage small molecule that activates p53 to kill cancer cells but not normal ones. Targeting Pol I provides the first path to selectively activating p53 in malignant but not normal, healthy cells. Similarly, Cylene's leadership in exploiting CK2-dependent pathways enabled the creation of the first-in-class, Phase II ready CX-4945 agent and CX-8184, the 2nd generation agent, that can serve as the drugs of choice in rational drug combinations for improved treatment outcomes against many cancer indications. Cylene's approach delivers agents that enable pharmaceutical companies to expand portfolios and extend the efficacy, lifecycle and reach of current cancer therapeutics.

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