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Ambient Clinical Analytics

Founded Year



Debt - II | Alive

Total Raised


Last Raised

$300K | 2 yrs ago

About Ambient Clinical Analytics

Ambient Clinical Analytics makes software tools that support hospital emergency rooms and intensive care units. It sells healthcare data assimilation, communication, and analytics-based decision support tools that support the ICU, Operating Room and Emergency Department. Its business model is supported by software license fees, SaaS, Cloud and system integration revenue.

Headquarters Location

221 First Avenue SW Suite 202

Rochester, Minnesota, 55902,

United States


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Ambient Clinical Analytics's Products & Differentiators

    AWARE Platform

    Ambient’s real time clinical analytics software provides operational and clinical efficiency by using licensed Mayo Clinic AI technologies, including over 1,200 algorithms that automates the planning for the patient’s care. Ambient’s AWARE™ is an FDA Class II, 510K cleared, and CE Mark registered software product for point of care use and was built by clinicians for clinicians. Ambient is one of the only companies offering Software as a Medical Device (SaaMD) that delivers point-of-care visualization to providers. It is the only EMR product that is indicative, predictive, and drives appropriate provider behavior for targeted treatments.

Expert Collections containing Ambient Clinical Analytics

Expert Collections are analyst-curated lists that highlight the companies you need to know in the most important technology spaces.

Ambient Clinical Analytics is included in 7 Expert Collections, including Value-Based Care & Population Health.


Value-Based Care & Population Health

1,066 items

The VBC & Population Health collection includes companies that enable and deliver care models that address the health needs for defining populations along the continuum of care, including in the community setting, through participation, engagement, and targeted interventions.


Medical Devices

11,721 items

Companies developing medical devices (per the IMDRF's definition of "medical device"). Includes software, lab-developed tests (LDTs), and combination products. *Columns updated as regularly as possible.


Conference Exhibitors

5,302 items


Digital Hospital

98 items

Startups recreating how healthcare is delivered


Digital Health

12,673 items

Technologies, platforms, and systems that engage consumers for lifestyle, wellness, or health-related purposes; capture, store, or transmit health data; and/or support life science and clinical operations. (DiME, DTA, HealthXL, & NODE.Health)


Health IT

10,238 items

This collection includes public and private companies, as well as startups, that market software solutions to healthcare provider organizations.

Latest Ambient Clinical Analytics News

Mayo Spin-Off Ambient Clinical Analytics Eyes Euro Markets with Dutch Backer

Mar 2, 2021

Noaber Foundation led a $1.5 million venture round for the digital health platform. As in its previous financings, Mayo Clinic Ventures was a participant – not surprising since the digital health start-up was co-founded by five Mayo clinicians using artificial intelligence technology licensed from the Rochester institution for its AWARE Critical Care clinical decision support system. But the new element this time is the participation a European venture partner: the Noaber Foundation of Lunteren, the Netherlands. The investment firm led the latest round and will be tapped to provide an entry into the European market for AWARE, Ambient CEO Allen Berning told TCB. “The Noaber Foundation and its venture investment arm, Noaber Ventures, were already acquainted with the digital health innovations coming out of the Mayo Clinic through their earlier investment in VitalHealth Software ,” he said. “And in our case, we were also really interested in establishing a sales and distribution network in Europe.”   A strong connection between Dutch investors and Mayo Clinic spin-offs was first demonstrated by VitalHealth, founded in 2006 as a joint venture between Mayo and the Noaber Foundation. A provider of cloud-based solutions for collaborative health management, its chairman was Mayo gastroenterologist and medical school professor Dr. Nicholas LaRusso, who was based in Minnesota, while its CEO was Laurens van der Tang, based in Amsterdam. In December, VitalHealth was sold to Dutch medical technology giant Royal Philips (NYSE: PHG) for an undisclosed amount. Like VitalHealth, Ambient Clinical Analytics is also a digital health firm spun off from Mayo Clinic research and already has a connection to Philips. Currently based in the Clinic’s downtown Rochester startup incubator, its product is the AWARE patient monitoring software, which aggregates and organizes once-scattered vital patient information into a single, easy-to-read interface, which it says results in reduced errors, lower health care costs, and better patient outcomes. Ambient first received FDA 510(k) pre-market clearance for AWARE (which stands for Ambient Warning and Response Evaluation) in 2015. The next year, Philips announced it was rolling out the AWARE dashboard, renamed the IntelliSpace Critical Care Console, as a key upgrade to its line of critical-care patient monitors. Now, with the Noaber venture investment, Berning said he’s aiming to tap his own experience at expansion into international markets initially honed during his stint as CEO of Rochester-based electronics manufacturer Pemstar Inc. during the 1990s and 2000s. “At Pemstar, we expanded into Europe and set up multiple facilities, first in the Netherlands through an acquisition there, and later into Ireland and Romania,” Berning said. “We were looking for an anchor partner with whom we could start working and who already understood the dynamics of the European health IT market.”   Along with Noaber and Mayo, early investors Social Capital and Bluestem Capital also joined the financing round. Meanwhile, Berning said Ambient is experiencing a bump in demand for its Sepsis DART product, which detects and provides digital guidance for treating sepsis, a potentially life-threatening complication of infection. That’s because the Centers for Medicare and Medicaid Services (CMS) is preparing to release new guidelines on quality-of-care measurements for reimbursing sepsis treatments and Ambient’s DART system is the only FDA-approved digital health solution for improving sepsis outcomes. Sepsis occurs when chemicals released into the bloodstream to fight the infection trigger inflammatory responses throughout the body. This inflammation can in turn cause multiple organ systems to fail, sometimes leading to death. “We have the ability to make sure the sepsis treatment can be completed during a three-to-six-hour time windows which will be called for under the CMS guidelines,” he said.

Ambient Clinical Analytics Frequently Asked Questions (FAQ)

  • When was Ambient Clinical Analytics founded?

    Ambient Clinical Analytics was founded in 2014.

  • Where is Ambient Clinical Analytics's headquarters?

    Ambient Clinical Analytics's headquarters is located at 221 First Avenue SW, Rochester.

  • What is Ambient Clinical Analytics's latest funding round?

    Ambient Clinical Analytics's latest funding round is Debt - II.

  • How much did Ambient Clinical Analytics raise?

    Ambient Clinical Analytics raised a total of $10.41M.

  • Who are the investors of Ambient Clinical Analytics?

    Investors of Ambient Clinical Analytics include Social Capital, Mayo Clinic Ventures, Bluestem Capital Partners, Waterline Ventures, Noaber Foundation and 4 more.

  • Who are Ambient Clinical Analytics's competitors?

    Competitors of Ambient Clinical Analytics include Clew and 2 more.

  • What products does Ambient Clinical Analytics offer?

    Ambient Clinical Analytics's products include AWARE Platform and 3 more.

Compare Ambient Clinical Analytics to Competitors

Autonomous Healthcare

Autonomous Healthcare is leveraging the power of machine learning and mathematical modeling to develop the technologies for critical care, non-invasive patient monitoring, and controlled-substance tracking.

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Decisio Health

Decisio Health is a clinical decision support platform designed for clinicians, with a focus on providing real-time, relevant data at the point of care. The company's mission is to improve clinical outcomes and reduce hospital healthcare costs. The Decisio Health Patient Dashboard is a Food and Drug Administration (FDA)-cleared, class II, software-based medical device that is entirely web-native.


Clew operates PiPPA services in Kyoto, Japan. PiPPA is a shared bike service that allows users to rent and return a bike and make a payment through one dedicated application. It was founded in 2021 and is based in Kyoto, Japan.

Philips Healthcare Informatics

Philips Healthcare Informatics was a Healthcare/Medical Facilities & Services company based in Foster City, California. Philips Healthcare Informatics was acquired in 2005.

Capsule Tech

Capsule Tech provides medical device connectivity solutions for hospitals that connect any medical device to any information system in any care area. The company has established partnerships with medical device manufacturers and installed enterprise-wide solutions in hospitals in a number of countries. On January 19th, 2021, Capsule Tech was acquired by Philips at a valuation of $635M.

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