ES Vascular Ltd. developed first ever surgical stapling devices for endovascular surgery. These devices aim to transform vascular surgery by shortening procedural times, and by simplifying and potentially increasing the safety of the most common vascular interventions. The company is currently developing three product lines for open AAA, endovascular AAA and Femoro-Pop bypass procedures. Its first products are anticipated to enter the market in 2008.nCompany Snapshotn Started in 2000 in Israel by Prof. Shifrin together with group of engineers and leading vascular surgeons from the US and Europe;n Developed a ever vascular stapling technology for stapling synthetic grafts to the aortan Developed endovascular devices for EVAR and SFA procedures

MediGuide is a medical-device company developing tracking and imaging technologies for use during minimally-invasive surgical procedures. Located in Haifa, Israel, MediGuide was established in 2001 as a spin-off of Elbit Systems (NASDAQ: ESLT), a major Israeli defense technology company. MediGuide has developed a highly sophisticated navigation system: Medical Positioning System ("gMPS"), which is aimed to enable real-time tracking of therapeutic and future diagnostic medical devices (gMPS Enabled Devices) such as catheters and stents equipped with miniature gMPS sensors. gMPS is intended to provide clinicians with 3-D information about the structure of the coronary arteries and to track gMPS-enabled devices in these vessels.

OrthoScan, Inc. manufactures the OrthoScan High Definition Mini C-Arm for extremity imaging. Designed for orthopedic surgeons, the small, lightweight C-arm configuration fluoroscopic system aims to provide real-time images with four times the resolution of other currently available fluoroscans. It can be used during surgical orthopedic procedures, and critical and emergency care procedures. OrthoScan, headquartered in Scottsdale, Arizona, uses state-of-the-art technologies to bring x-ray imaging in extremity surgery to a next level. For instance, innovative flat detectors in the latest product introduction named OrthoScan HD, allows reduction of distortions inherent with previous image intensifier technology, thereby improving significantly diagnostic accuracy. The mini C-Arms by OrthoScan provide the solution needed by orthopaedics and podiatrists for high-quality imaging in a small-scale device, facilitating complex surgeries on small and delicate body structures, such as wrists, knees and ankles. In September 2011, Orthoscan was acquired Aton, a German private investment firm. Orthoscan's valuation was not disclosed.

VasoLux MicroSystems, LLC has developed a diagnostic imaging system to help surgeons identify later-stage osteoarthritis patients who are best suited for cartilage repair procedures or joint replacement surgery.

CardioMag Imaging (CMI) is a medical device company that is engaged in the development and commercialization of a kind of cardiac diagnostic device known as MagnetoCardioGraphs (MCG). The device the company has developed consists of the integration of highly sophisticated sensors, electronics, and software. The company's MCG system is a non-invasive cardiac medical diagnostic device that aims to provide clinically relevant information about heart function without use of ionizing radiation. CardioMag's MCG system is a MCG system to obtain FDA approval.

Rafael Medical has developed a novel anchoring system for safely implanting and retrieving a wide range of intra-vascular devices in a minimally invasive manner. Based on the technology, diagnostic and therapeutic devices can be delivered into small and large blood vessels alike by way of a small-sized delivery system. Following the completion of the SafeFlo Filter the company is now developing additional devices geared to the interventional cardiology market.